Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
Iron homeostasis and organismal aging
Iron is indispensable for normal body functions across species because of its critical roles in
red blood cell function and many essential proteins and enzymes required for numerous …
red blood cell function and many essential proteins and enzymes required for numerous …
Iron homeostasis in health and disease
Iron is required for the survival of most organisms, including bacteria, plants, and humans. Its
homeostasis in mammals must be fine-tuned to avoid iron deficiency with a reduced oxygen …
homeostasis in mammals must be fine-tuned to avoid iron deficiency with a reduced oxygen …
Diadzein ameliorates 5-fluorouracil-induced intestinal mucositis by suppressing oxidative stress and inflammatory mediators in rodents
Fluorouracil (5-FU) is one of the most commonly prescribed anti-cancer agent. However, its
use is associated with several debilitating adverse effects such as intestinal mucositis (IM) …
use is associated with several debilitating adverse effects such as intestinal mucositis (IM) …
Potential use of superparamagnetic iron oxide nanoparticles for in vitro and in vivo bioimaging of human myoblasts
KR Wierzbinski, T Szymanski, N Rozwadowska… - Scientific reports, 2018 - nature.com
Myocardial infarction (MI) is one of the most frequent causes of death in industrialized
countries. Stem cells therapy seems to be very promising for regenerative medicine. Skeletal …
countries. Stem cells therapy seems to be very promising for regenerative medicine. Skeletal …
Anti-neuropathic pain activity of Ajugarin-I via activation of Nrf2 signaling and inhibition of TRPV1/TRPM8 nociceptors in STZ-induced diabetic neuropathy
This study aimed to investigate the anti-neuropathic pain activity and its underlying
molecular mechanism of Ajugarin-I (Aju-I) in a rat model of diabetic neuropathic pain. The …
molecular mechanism of Ajugarin-I (Aju-I) in a rat model of diabetic neuropathic pain. The …
The association between dietary nutrient intake and acceleration of aging: evidence from NHANES
J Ma, P Li, Y Jiang, X Yang, Y Luo, L Tao, X Guo… - Nutrients, 2024 - mdpi.com
The acceleration of aging is a risk factor for numerous diseases, and diet has been identified
as an especially effective anti-aging method. Currently, research on the relationship …
as an especially effective anti-aging method. Currently, research on the relationship …
Neuroprotective mechanism of Ajugarin-I against Vincristine-Induced neuropathic pain via regulation of Nrf2/NF-κB and Bcl2 signalling
Vincristine (VCR) is a well-known chemotherapeutic agent that frequently triggers
neuropathic pain. Ajugarin-I (Aju-I) isolated from Ajuga bracteosa exerts antioxidant, anti …
neuropathic pain. Ajugarin-I (Aju-I) isolated from Ajuga bracteosa exerts antioxidant, anti …
[HTML][HTML] Cardiac iron metabolism during aging–Role of inflammation and proteolysis
Iron is the most abundant trace element in the human body. Since iron can switch between
its 2-valent and 3-valent form it is essential in various physiological processes such as …
its 2-valent and 3-valent form it is essential in various physiological processes such as …
The Hog1 MAPK substrate governs Candida glabrata-epithelial cell adhesion via the histone H2A variant
MS Sahu, R Purushotham, R Kaur - PLoS Genetics, 2024 - journals.plos.org
CgHog1, terminal kinase of the high-osmolarity glycerol signalling pathway, orchestrates
cellular response to multiple external stimuli including surplus-environmental iron in the …
cellular response to multiple external stimuli including surplus-environmental iron in the …