Pancreatic cancer is a highly malignant digestive system tumor with a poor prognosis. Most
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to …

Pancreatic cancer (PC) is a leading cause of cancer related mortality on a global scale. The
disease itself is associated with a dismal prognosis, partly due to its silent nature resulting in …

In recent years, a growing number of studies have evaluated the role of exosomes in
pancreatic ductal adenocarcinoma cancer (PDAC) demonstrating their involvement in a …

Abstract Ca 2+ binding proteins (CBP) are of key importance for calcium to play its role as a
pivotal second messenger. CBP bind Ca 2+ in specific domains, contributing to the …

Pancreatic cancer is one of the most fatal malignancies, as approximately 80% of patients
are at advanced stages by the time of diagnosis. The main reason for the poor overall …

In this work, we have prepared peptide-functionalized metal-organic frameworks (MOFs) as
signal-amplifying tags for the detection of secreted protein acidic and rich in cysteine …

Pancreatic cancer (PC) is an increasing cause of cancer-related death, with a dismal
prognosis caused by its aggressive biology, the lack of clinical symptoms in the early phases …

Secreted protein acidic and rich in cysteine (SPARC) is expressed in diverse tissues and
plays roles in various biological functions and processes. Increased serum levels of SPARC …

Cancer is a complex disease with high incidence and mortality rates. The important role
played by the tumor microenvironment in regulating oncogenesis, tumor growth, and …

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest of all solid tumours and
more effective therapy is urgently needed. The stroma is thought to play a critical role in …