The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

The rectal route is an effective route for the local and systemic delivery of active
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …

The human eye is a complex organ with unique anatomy and physiology that restricts the
delivery of drugs to target ocular tissues/sites. Recent advances in the field of pharmacy …

As an effective anti-HIV drug, cabotegravir (CAB) is currently administered via oral and
injection routes, leading to several drawbacks, such as poor oral bioavailability and …

Alzheimer's disease (AD) often leads to dementia, causing cognitive decline and increased
care needs. Rivastigmine (RV) is a key AD treatment, but its brain delivery is limited by the …

The efficacy of orally delivered medicines can be maximized through enhancing the gastric
residence period and modifying the drug release pattern according to therapeutic need …

Currently, periodontitis is treated by oral dosage forms (antibiotics) which shows systemic
side effects and failed to reach the therapeutic concentration (above minimum inhibitory …

This study aimed to develop a thermosensitive in situ gel formulation for rectal delivery of
Ibuprofen as an efficient alternative dosage form. Utilizing poloxamer 188, poloxamer 407 …

The present study aimed to prepare, characterize, and evaluate a thermo-responsive sol–
gel for intranasal delivery of lamotrigine (LTG), which was designed for sustained drug …

Babies born to mothers suffering from gonorrhea may experience severe eye infections that
might culminate in loss of vision. The eyes of the neonate can are infected with Neisseria …