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Basal forebrain cholinergic circuits and signaling in cognition and cognitive decline
Recent work continues to place cholinergic circuits at center stage for normal executive and
mnemonic functioning and provides compelling evidence that the loss of cholinergic …
mnemonic functioning and provides compelling evidence that the loss of cholinergic …
Cholinergic modulation of the hippocampal region and memory function
J Haam, JL Yakel - Journal of neurochemistry, 2017 - Wiley Online Library
Acetylcholine (AC h) plays an important role in memory function and has been implicated in
aging‐related dementia, in which the impairment of hippocampus‐dependent learning …
aging‐related dementia, in which the impairment of hippocampus‐dependent learning …
An improved neuroanatomical model of the default-mode network reconciles previous neuroimaging and neuropathological findings
The brain is constituted of multiple networks of functionally correlated brain areas, out of
which the default-mode network (DMN) is the largest. Most existing research into the DMN …
which the default-mode network (DMN) is the largest. Most existing research into the DMN …
Neuronal circuitry for recognition memory of object and place in rodent models
Rats and mice are used for studying neuronal circuits underlying recognition memory due to
their ability to spontaneously remember the occurrence of an object, its place and an …
their ability to spontaneously remember the occurrence of an object, its place and an …
Cholinergic suppression of hippocampal sharp-wave ripples impairs working memory
Learning and memory are assumed to be supported by mechanisms that involve cholinergic
transmission and hippocampal theta. Using G protein–coupled receptor-activation–based …
transmission and hippocampal theta. Using G protein–coupled receptor-activation–based …
Specific basal forebrain–cortical cholinergic circuits coordinate cognitive operations
Based on recent molecular genetics, as well as functional and quantitative anatomical
studies, the basal forebrain (BF) cholinergic projections, once viewed as a diffuse system …
studies, the basal forebrain (BF) cholinergic projections, once viewed as a diffuse system …
Interneuronal mechanisms of hippocampal theta oscillations in a full-scale model of the rodent CA1 circuit
The hippocampal theta rhythm plays important roles in information processing; however, the
mechanisms of its generation are not well understood. We developed a data-driven …
mechanisms of its generation are not well understood. We developed a data-driven …
[HTML][HTML] Acetylcholine bidirectionally regulates learning and memory
Q Huang, C Liao, F Ge, J Ao, T Liu - Journal of Neurorestoratology, 2022 - Elsevier
Acetylcholine (ACh) is one of the most important neurotransmitters in the central cholinergic
system; it specifically binds to muscarinic and nicotinic receptors and is degraded by …
system; it specifically binds to muscarinic and nicotinic receptors and is degraded by …
Molecularly defined and functionally distinct cholinergic subnetworks
X Li, H Yu, B Zhang, L Li, W Chen, Q Yu, X Huang… - Neuron, 2022 - cell.com
Cholinergic neurons in the medial septum (MS) constitute a major source of cholinergic
input to the forebrain and modulate diverse functions, including sensory processing …
input to the forebrain and modulate diverse functions, including sensory processing …
Supramammillary regulation of locomotion and hippocampal activity
Locomotor speed is a basic input used to calculate one's position, but where this signal
comes from is unclear. We identified neurons in the supramammillary nucleus (SuM) of the …
comes from is unclear. We identified neurons in the supramammillary nucleus (SuM) of the …