Complex biological systems and cellular networks may underlie most genotype to
phenotype relationships. Here, we review basic concepts in network biology, discussing …

Network medicine is an emerging area of research dealing with molecular and genetic
interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale …

Nitrogen is an essential macronutrient for plant growth and basic metabolic processes. The
application of nitrogen-containing fertilizer increases yield, which has been a substantial …

Wild almond species accumulate the bitter and toxic cyanogenic diglucoside amygdalin.
Almond domestication was enabled by the selection of genotypes harboring sweet kernels …

In any given cell, thousands of genes are expressed and work in concert to ensure the cell's
function, fitness, and survival. Each gene, in turn, must be expressed at the proper time and …

Jasmonates (JAs) are plant-specific signaling molecules that steer a diverse set of
physiological and developmental processes. Pathogen attack and wounding inflicted by …

Fat is stored or mobilized according to food availability. Malfunction of the mechanisms that
ensure this coordination underlie metabolic diseases in humans. In mammals, lysosomal …

The Gateway® cloning system sets a new trend in molecular biology by addressing the
difficulties of adaptability, efficiency and compatibility of the traditional cloning approaches …

The recent establishment of recombination‐based cloning systems has greatly facilitated the
analysis of gene function by allowing rapid and high‐efficiency generation of plasmid …

Next-generation sequencing has not been applied to protein-protein interactome network
map** so far because the association between the members of each interacting pair …