A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …

Tyrosinase is a multifunctional, glycosylated, and copper-containing oxidase, which
catalyzes the first two steps in mammalian melanogenesis and is responsible for enzymatic …

The more recent reports on polyphenol oxidase in plants and fungi are reviewed. The main
aspects considered are the structure, distribution, location and properties of polyphenol …

Tyrosinase plays a pivotal role in the synthesis of melanin pigment synthesis on skin utilizing
tyrosine as a substrate. Melanin is responsible for the protection against harmful ultraviolet …

Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles: A Review of the
Literature from 2000–2012 Next Article in Journal Chemical Composition of Essential Oil …

Due to its integral role in the biosynthesis of melanin in all kingdoms of life, tyrosinase has
become an extremely important target for inhibition in several sectors of research including …

Tyrosinase is a copper-containing oxidation enzyme, which is responsible for the production
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …

The synthetic strategies and characterization of some novel 1, 3, 4-oxadiazole derivatives
carrying different pharmacophores and heterocyclic rings that are relevant to potential …

Abstract Five member heterocyclic 1, 3, 4-oxadiazole nucleus find unique place in medicinal
chemistry and plays significant role in producing anticancer activity. The small and simple 1 …

The world's health system is plagued by cancer and a worldwide effort is underway to find
new drugs to treat cancer. There has been a significant improvement in understanding the …