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Reviving the transcriptome studies: an insight into the emergence of single-molecule transcriptome sequencing
Advances in transcriptomics have provided an exceptional opportunity to study functional
implications of the genetic variability. Technologies such as RNA-Seq have emerged as …
implications of the genetic variability. Technologies such as RNA-Seq have emerged as …
OcculterCut: a comprehensive survey of AT-rich regions in fungal genomes
We present a novel method to measure the local GC-content bias in genomes and a survey
of published fungal species. The method, enacted as “OcculterCut”(https://sourceforge …
of published fungal species. The method, enacted as “OcculterCut”(https://sourceforge …
GeMoMa: homology-based gene prediction utilizing intron position conservation and RNA-seq data
J Keilwagen, F Hartung, J Grau - Gene prediction: Methods and protocols, 2019 - Springer
GeMoMa is a homology-based gene prediction program that predicts gene models in target
species based on gene models in evolutionary related reference species. GeMoMa utilizes …
species based on gene models in evolutionary related reference species. GeMoMa utilizes …
BRAKER1: unsupervised RNA-Seq-based genome annotation with GeneMark-ET and AUGUSTUS
Motivation: Gene finding in eukaryotic genomes is notoriously difficult to automate. The task
is to design a work flow with a minimal set of tools that would reach state-of-the-art …
is to design a work flow with a minimal set of tools that would reach state-of-the-art …
Environmental gradients reveal stress hubs pre-dating plant terrestrialization
A Dadras, JMR Fürst-Jansen, T Darienko, D Krone… - Nature Plants, 2023 - nature.com
Plant terrestrialization brought forth the land plants (embryophytes). Embryophytes account
for most of the biomass on land and evolved from streptophyte algae in a singular event …
for most of the biomass on land and evolved from streptophyte algae in a singular event …
The pan-genome of Aspergillus fumigatus provides a high-resolution view of its population structure revealing high levels of lineage-specific diversity driven by …
Aspergillus fumigatus is a deadly agent of human fungal disease where virulence
heterogeneity is thought to be at least partially structured by genetic variation between …
heterogeneity is thought to be at least partially structured by genetic variation between …
Combining RNA-seq data and homology-based gene prediction for plants, animals and fungi
J Keilwagen, F Hartung, M Paulini, SO Twardziok… - BMC …, 2018 - Springer
Background Genome annotation is of key importance in many research questions. The
identification of protein-coding genes is often based on transcriptome sequencing data, ab …
identification of protein-coding genes is often based on transcriptome sequencing data, ab …
Emergence of the Ug99 lineage of the wheat stem rust pathogen through somatic hybridisation
Parasexuality contributes to diversity and adaptive evolution of haploid (monokaryotic) fungi.
However, non-sexual genetic exchange mechanisms are not defined in dikaryotic fungi …
However, non-sexual genetic exchange mechanisms are not defined in dikaryotic fungi …
The Complete Genome Sequence of the Phytopathogenic Fungus Sclerotinia sclerotiorum Reveals Insights into the Genome Architecture of Broad Host Range …
M Derbyshire, M Denton-Giles… - Genome biology and …, 2017 - academic.oup.com
Sclerotinia sclerotiorum is a phytopathogenic fungus with over 400 hosts including
numerous economically important cultivated species. This contrasts many economically …
numerous economically important cultivated species. This contrasts many economically …
A benchmark study of ab initio gene prediction methods in diverse eukaryotic organisms
Background The draft genome assemblies produced by new sequencing technologies
present important challenges for automatic gene prediction pipelines, leading to less …
present important challenges for automatic gene prediction pipelines, leading to less …