Lithium remains the drug of first choice for prophylactic treatment of bipolar disorder,
preventing the recurrences of manic and depressive episodes. The longitudinal experiences …

Aging is a dynamic and progressive process that begins at conception and continues until
death. This process leads to a decrease in homeostasis and morphological, biochemical …

Neurodegeneration is a pathological process characterized by progressive neuronal
impairment, dysfunction, and loss due to mitochondrial dysfunction, oxidative stress …

Over the last six decades, lithium has been considered the gold standard treatment for the
long-term management of bipolar disorder due to its efficacy in preventing both manic and …

Lithium is associated with oxidative stress and apoptosis, but the mechanism by which
lithium protects against spinal cord injury remains poorly understood. In this study, we found …

Metallodrugs correspond to a small portion of all available drugs in the market and, yet,
some of them are among the most used and important drugs in modern medicine. However …

Zusammenfassung Die Verordnungsstruktur der Psychopharmaka hat sich in den letzten 10
Jahren auffällig verändert. Die Verordnungen der früher führenden Tranquillantien haben …

The use of lithium for the prevention of recurrences in mood disorders has a 55-year history.
Nowadays, lithium is universally accepted as the first-choice mood-stabilizer (MS) for …

Stroke causes degeneration and death of neurones leading to the loss of motor function and
frequent occurrence of cognitive impairment and depression. Lithium (Li+), the archetypal …

This paper discusses essential issues related to long-term lithium therapy and presents a
case of successful 50-year lithium treatment. Lithium is currently regarded as the drug of …