Role of LGMN in tumor development and its progression and connection with the tumor microenvironment

SU Khan, IM Khan, MU Khan, MA Ud Din… - Frontiers in Molecular …, 2023 - frontiersin.org
Legumain (LGMN) has been demonstrated to be overexpressed not just in breast, prostatic,
and liver tumor cells, but also in the macrophages that compose the tumor …

Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway

X Zhang, S Wang, H Wang, J Cao, X Huang, Z Chen… - Molecular cancer, 2019 - Springer
Background CircRNA has emerged as a new non-coding RNA that plays crucial roles in
tumour initiation and development.'MiRNA sponge'is the most reported role played by …

The function and mechanisms of action of LOXL2 in cancer

L Wu, Y Zhu - International journal of molecular …, 2015 - spandidos-publications.com
The lysyl oxidase (LOX) family is comprised of five members, and some members have
recently emerged as important regulators of tumor progression. Among these, at present …

The long non-coding RNA TUG1 indicates a poor prognosis for colorectal cancer and promotes metastasis by affecting epithelial-mesenchymal transition

J Sun, C Ding, Z Yang, T Liu, X Zhang, C Zhao… - Journal of translational …, 2016 - Springer
Background Long intergenic non-coding RNAs (lncRNAs) are a class of non-coding RNAs
that are involved in gene expression regulation. Taurine up-regulated gene 1 (TUG1) is a …

Role of the extracellular matrix in cancer‐associated epithelial to mesenchymal transition phenomenon

G Tzanakakis, RM Kavasi, K Voudouri… - Developmental …, 2018 - Wiley Online Library
The epithelial to mesenchymal transition (EMT) program is a crucial component in the
processes of morphogenesis and embryonic development. The transition of epithelial to …

BCL6 induces EMT by promoting the ZEB1-mediated transcription repression of E-cadherin in breast cancer cells

JM Yu, W Sun, F Hua, J **e, H Lin, DD Zhou, ZW Hu - Cancer letters, 2015 - Elsevier
Abstract B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor, is involved in the
development and progression of breast cancers with uncertain mechanism. The purpose of …

[HTML][HTML] Zileuton™ loaded in polymer micelles effectively reduce breast cancer circulating tumor cells and intratumoral cancer stem cells

P Gener, S Montero, H Xandri-Monje… - … , Biology and Medicine, 2020 - Elsevier
Tumor recurrence, metastatic spread and progressive gain of chemo-resistance of advanced
cancers are sustained by the presence of cancer stem cells (CSCs) within the tumor …

Effects of Scutellaria barbata polysaccharide on the proliferation, apoptosis and EMT of human colon cancer HT29 Cells

P Sun, D Sun, X Wang - Carbohydrate polymers, 2017 - Elsevier
A water-soluble polysaccharide SPS2p was isolated from the whole grass of Scutellaria
barbata and SPS2p contained 53.6% carbohydrates, 38.5% uronic acid and 8.2% proteins …

RNAi-mediated control of aflatoxins in peanut: method to analyze mycotoxin production and transgene expression in the peanut/Aspergillus pathosystem

RS Arias, PM Dang, VS Sobolev - Journal of visualized …, 2015 - pmc.ncbi.nlm.nih.gov
The Food and Agriculture Organization of the United Nations estimates that 25% of the food
crops in the world are contaminated with aflatoxins. That represents 100 million tons of food …

PI3K/Akt/HIF-1α signaling pathway mediates HPV-16 oncoprotein-induced expression of EMT-related transcription factors in non-small cell lung cancer cells

J Liu, B Huang, Z **u, Z Zhou, J Liu, X Li… - Journal of …, 2018 - pmc.ncbi.nlm.nih.gov
Background: Our previous studies have demonstrated that human papillomaviruse (HPV)-16
oncoproteins promoted epithelial-mesenchymal transition (EMT), leading to non-small cell …