In recent years, the worldwide spread of the so-called high-risk clones of multidrug-resistant
or extensively drug-resistant (MDR/XDR) Pseudomonas aeruginosa has become a public …

Pseudomonas aeruginosa is an opportunistic pathogen affecting immunocompromised
patients. It is known as the leading cause of morbidity and mortality in cystic fibrosis (CF) …

Infections that involve interkingdom microbial communities, such as those between bacteria
and yeast pathogens, are difficult to treat, associated with worse patient outcomes, and may …

After the first discovery in the 1980s in F-plasmids as a plasmid maintenance system, a
myriad of toxin-antitoxin (TA) systems has been identified in bacterial chromosomes and …

Toxin-antitoxin (TA) modules are ubiquitous gene loci among bacteria and are comprised of
a toxin part and its cognate antitoxin part. Under normal physiological conditions, antitoxin …

Pathogens that infect the gastrointestinal and respiratory tracts are subjected to intense
pressure due to the environmental conditions of the surroundings. This pressure has led to …

Bacterial virulence relies on a delicate balance of signals interchanged between the
invading microbe and the host. This communication has been extensively perceived as a …

Toxin-antitoxin (TA) systems are prevalent in bacteria and archaea. Although not essential
for normal cell growth, TA systems are implicated in multiple cellular functions associated …

Persister cell (PC) is dormant, tolerant to antibiotics, and a transient reversible phenotype.
These phenotypes are observed in P. aeruginosa and cause bacterial chronic infection as …

For plants, the advantages of associating with beneficial bacteria include plant growth
promotion, reduction of abiotic and biotic stresses and enhanced protection against various …