Parkinson's disease: from pathogenesis to pharmacogenomics
R Cacabelos - International journal of molecular sciences, 2017 - mdpi.com
Parkinson's disease (PD) is the second most important age-related neurodegenerative
disorder in developed societies, after Alzheimer's disease, with a prevalence ranging from …
disorder in developed societies, after Alzheimer's disease, with a prevalence ranging from …
New era of artificial intelligence and machine learning-based detection, diagnosis, and therapeutics in Parkinson's disease
Parkinson's disease (PD) is characterized by the loss of neuronal cells, which leads to
synaptic dysfunction and cognitive defects. Despite the advancements in treatment …
synaptic dysfunction and cognitive defects. Despite the advancements in treatment …
A perspective on Nrf2 signaling pathway for neuroinflammation: a potential therapeutic target in Alzheimer's and Parkinson's diseases
Neuroinflammation plays a pivotal role in Alzheimer's disease (AD) and Parkinson's disease
(PD), the leading causes of dementia. These neurological disorders are characterized by the …
(PD), the leading causes of dementia. These neurological disorders are characterized by the …
Role of Nrf2 in aging, Alzheimer's and other neurodegenerative diseases
Abstract Nuclear Factor-Erythroid Factor 2 (Nrf2) is an important transcription factor that
regulates the expression of large number of genes in healthy and disease states. Nrf2 is …
regulates the expression of large number of genes in healthy and disease states. Nrf2 is …
Development of a biochemical diagnosis of Parkinson disease by detection of α-synuclein misfolded aggregates in cerebrospinal fluid
Importance Parkinson disease (PD) is a highly prevalent and incurable neurodegenerative
disease associated with the accumulation of misfolded α-synuclein (αSyn) aggregates. An …
disease associated with the accumulation of misfolded α-synuclein (αSyn) aggregates. An …
[HTML][HTML] Neurotoxicity of pesticides–A link to neurodegeneration
B Vellingiri, M Chandrasekhar, SS Sabari… - Ecotoxicology and …, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder which mainly targets motor
symptoms such as tremor, rigidity, bradykinesia and postural instability. The physiological …
symptoms such as tremor, rigidity, bradykinesia and postural instability. The physiological …
Pathophysiology of motor dysfunction in Parkinson's disease as the rationale for drug treatment and rehabilitation
Cardinal motor features of Parkinson's disease (PD) include bradykinesia, rest tremor, and
rigidity, which appear in the early stages of the disease and largely depend on …
rigidity, which appear in the early stages of the disease and largely depend on …
Emergence of extracellular vesicles as “liquid biopsy” for neurological disorders: boom or bust
Extracellular vesicles (EVs) have emerged as an attractive liquid biopsy approach in the
diagnosis and prognosis of multiple diseases and disorders. The feasibility of enriching …
diagnosis and prognosis of multiple diseases and disorders. The feasibility of enriching …
Dietary polyphenols—Important non-nutrients in the prevention of chronic noncommunicable diseases. A systematic review
W Koch - Nutrients, 2019 - mdpi.com
The improvement of the social and economic conditions of society has eliminated the threat
of death from the majority of infectious diseases. However, the rapid progress of civilization …
of death from the majority of infectious diseases. However, the rapid progress of civilization …
Pathophysiology and therapeutic perspectives of oxidative stress and neurodegenerative diseases: a narrative review
Introduction Neurodegeneration is the term describing the death of neurons both in the
central nervous system and periphery. When affecting the central nervous system, it is …
central nervous system and periphery. When affecting the central nervous system, it is …