Understanding large scale sequencing datasets through changes to protein folding
D Shorthouse, H Lister, GS Freeman… - Briefings in Functional …, 2024 - academic.oup.com
The expansion of high-quality, low-cost sequencing has created an enormous opportunity to
understand how genetic variants alter cellular behaviour in disease. The high diversity of …
understand how genetic variants alter cellular behaviour in disease. The high diversity of …
[HTML][HTML] Impacts of SARS-CoV-2 on diabetes mellitus: A pre and post pandemic evaluation
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by the novel beta
coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) crippled the …
coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) crippled the …
Distinctive features of the XBB. 1.5 and XBB. 1.16 spike protein receptor-binding domains and their roles in conformational changes and angiotensin-converting …
The emergence and the high transmissibility of the XBB. 1.5 and XBB. 1.16 subvariants of
the SARS-CoV-2 omicron has reignited concerns over the potential impact on vaccine …
the SARS-CoV-2 omicron has reignited concerns over the potential impact on vaccine …
[HTML][HTML] Impact of African-Specific ACE2 Polymorphisms on Omicron BA. 4/5 RBD Binding and Allosteric Communication Within the ACE2–RBD Protein Complex
Severe acute respiratory symptom coronavirus 2 (SARS-CoV-2) infection occurs via the
attachment of the spike (S) protein's receptor binding domain (RBD) to human ACE2 …
attachment of the spike (S) protein's receptor binding domain (RBD) to human ACE2 …
Bioinformatics analysis to identify the relationship between human papillomavirus-associated cervical cancer, toll-like receptors and exomes: A genetic epidemiology …
FC Gomes, DR Galhardo, ACG Navegante, GS Santos… - Plos one, 2024 - journals.plos.org
Introduction Genetic variants may influence Toll-like receptor (TLR) signaling in the immune
response to human papillomavirus (HPV) infection and lead to cervical cancer. In this study …
response to human papillomavirus (HPV) infection and lead to cervical cancer. In this study …
Intronic Variants of the Angiotensin‐Converting Enzyme 2 Gene Modulate Plasma ACE2 Levels and Possibly Confer Protection against Severe COVID‐19
Membrane‐bound angiotensin‐converting enzyme 2 (ACE2) receptor acts as the entry point
for the novel coronavirus, SARS‐CoV‐2. Polymorphisms in the ACE2 gene may alter viral …
for the novel coronavirus, SARS‐CoV‐2. Polymorphisms in the ACE2 gene may alter viral …
The emergence of a novel SARS-CoV-2 variant with higher efficiency of binding with the human host cell receptors in Iraqi subjects
The objective of this study was to assess the impact of variations in the surface glycoprotein
of SARS-CoV-2, which is generated by the spike (S) gene, on its interaction with host …
of SARS-CoV-2, which is generated by the spike (S) gene, on its interaction with host …
Missense variant rs75603675 within TMPRSS2 gene is associated with the increased risk of severe form of COVID-19
Host genetics among other factors play an important role in COVID-19 disease severity.
TMPRSS2, a serine protease, facilitates the priming of the SARS-CoV-2 spike protein, which …
TMPRSS2, a serine protease, facilitates the priming of the SARS-CoV-2 spike protein, which …
Classification of Single-Nucleotide Polymorphisms (SNPs): Tips from the Basic Knowledge to the Clinical Outcomes
MBS Al-Shuhaib - 2024 - Springer
Single-nucleotide polymorphisms (SNPs) are the cornerstone of individuals' variations in
sensitivity to cancer and drugs. The necessity of understanding how SNPs work is an urgent …
sensitivity to cancer and drugs. The necessity of understanding how SNPs work is an urgent …
Whale Optimization Algorithm for Medical Diagnostic: A Systematic Literature Review
F Septian, E Utami - SISKOMTI (Sistem Informasi Komputer …, 2022 - ejournal.uniled.ac.id
A lot of factors, including noise, have a harmful impact on the health of people from all walks
of life, including unborn children. In the medical field, grou** research utilizing WOA was …
of life, including unborn children. In the medical field, grou** research utilizing WOA was …