Lipid-based nanoparticles for psoriasis treatment: A review on conventional treatments, recent works, and future prospects

UUM Nordin, N Ahmad, N Salim, NSM Yusof - RSC advances, 2021‏ - pubs.rsc.org
Psoriasis is a lingering inflammatory skin disease that attacks the immune system. The
abnormal interactions between T cells, immune cells, and inflammatory cytokines causing …

Potential role of cytochrome c and tryptase in psoriasis and psoriatic arthritis pathogenesis: focus on resistance to apoptosis and oxidative stress

MS Chimenti, F Sunzini, L Fiorucci, E Botti… - Frontiers in …, 2018‏ - frontiersin.org
Psoriasis (PsO) is an autoimmune disease characterized by keratinocyte proliferation,
chronic inflammation and mast cell activation. Up to 42% of patients with PsO may present …

Piperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation

S Thatikonda, V Pooladanda, DK Sigalapalli… - Cell death & …, 2020‏ - nature.com
Psoriasis is an autoimmune skin disease, where chronic immune responses due to
exaggerated cytokine signaling, abnormal differentiation, and evasion of keratinocytes …

CD44 targeted indirubin nanocrystal-loaded hyaluronic acid hydrogel for the treatment of psoriasis

L Li, C Liu, J Fu, Y Wang, D Yang, B Peng, X Liu… - International Journal of …, 2023‏ - Elsevier
Despite advances in transdermal drug delivery for treating psoriasis, there are still unmet
medical needs, hyaluronic acid (HA)-based topical formulations as nanocarriers, which can …

Sponge‐Like Microneedles Spatially Sequester Chemokines and Deplete Monocytes to Alleviate Inflammatory Skin Disorders

Z Le, Y Shou, RR Li, L Liu, R Tan… - Advanced Functional …, 2024‏ - Wiley Online Library
Persistent inflammation, characterized by the intense interplay of inflammatory chemokine
secretion and immune cell infiltration, is a hallmark of many skin disorders including diabetic …

Etiopathogenesis of Psoriasis: Integration of Proposed Theories

BF Hernandez-Nicols, JJ Robledo-Pulido… - Immunological …, 2024‏ - Taylor & Francis
Psoriasis is a chronic inflammatory disease characterized by squamous and erythematous
plaques on the skin and the involvement of the immune system. Global prevalence for …

Polydopamine/IR820 nanoparticles as topical phototheranostics for inhibiting psoriasiform lesions through dual photothermal and photodynamic treatments

GR Nirmal, ZC Lin, CH Lin, CT Sung, CC Liao… - Biomaterials …, 2022‏ - pubs.rsc.org
Dual photothermal and photodynamic therapy (PTT and PDT) is an attractive approach that
generates a synergistic effect for inhibiting keratinocyte hyperproliferation in the treatment of …

[HTML][HTML] Silencing of HMGA2 by siRNA loaded methotrexate functionalized polyamidoamine dendrimer for human breast cancer cell therapy

F Abedi Gaballu, WCS Cho, G Dehghan, A Zarebkohan… - Genes, 2021‏ - mdpi.com
The transcription factor high mobility group protein A2 (HMGA2) plays an important role in
the pathogenesis of some cancers including breast cancer. Polyamidoamine dendrimer …

An inulin-type polysaccharide from Atractylodis Macrocephalae Rhizoma can relieve psoriasis

X Tang, L Liu, Y Wu, Y Zhao, C Lu, R Zhao - International Journal of …, 2024‏ - Elsevier
Abstract Atractylodis Macrocephalae Rhizoma (AMR), an herb often found in compounded
remedies for psoriasis, is rich in polysaccharides. However, the beneficial effects of AMR …

Elevated IL-22 in psoriasis plays an anti-apoptotic role in keratinocytes through mediating Bcl-xL/Bax

B Wang, D Han, F Li, W Hou, L Wang, L Meng, K Mou… - Apoptosis, 2020‏ - Springer
IL-22 is known to mediate inflammation in psoriasis, while IL-22 binding protein (IL-22BP)
binds IL-22 to suppress IL-22 signaling. However, the function of IL-22 in regulating …