The effect of membrane transporters on drug disposition, efficacy and safety is now well
recognized. Since the initial publication from the International Transporter Consortium …

Members of the solute carrier organic anion transporting polypeptide (OATPs) family
function as transporters for a large variety of amphipathic organic anions including …

Introduction Membrane transporters are now widely recognized for their role in the
absorption, distribution, clearance, and elimination of drugs. The organic cation transporters …

Organic cations comprise a significant part of medically relevant drugs and endogenous
substances. Such substances need organic cation transporters for efficient transfer via cell …

Membrane transporters play a fundamental role in the tissue distribution of endogenous
compounds and xenobiotics and are major determinants of efficacy and side effects profiles …

Stereoselectivity can be most relevant in drug metabolism and receptor binding. Although
drug membrane transport might be equally important for small-molecule pharmacokinetics …

Inflammation is a physiological condition characterized by a complex interplay between
different cells handled by metabolites and specific inflammatory-related molecules. In some …

Drug transporters are membrane proteins known for their role in handling pharmaceutical
products. However, recent work suggests they contribute to physiology by transporting …