The genetics of stress-related disorders: PTSD, depression, and anxiety disorders

JW Smoller - Neuropsychopharmacology, 2016 - nature.com
Research into the causes of psychopathology has largely focused on two broad etiologic
factors: genetic vulnerability and environmental stressors. An important role for …

[HTML][HTML] Obesity and depression: its prevalence and influence as a prognostic factor: a systematic review

BV Blasco, J García-Jiménez, I Bodoano… - Psychiatry …, 2020 - ncbi.nlm.nih.gov
Objective Depression and obesity are two conditions with great impact over global health.
This is mainly due to their high prevalence and the morbidity and mortality associated to …

The genetic overlap between mood disorders and cardiometabolic diseases: a systematic review of genome wide and candidate gene studies

AT Amare, KO Schubert, M Klingler-Hoffmann… - Translational …, 2017 - nature.com
Meta-analyses of genome-wide association studies (meta-GWASs) and candidate gene
studies have identified genetic variants associated with cardiovascular diseases, metabolic …

Is there a “metabolic-mood syndrome”? A review of the relationship between obesity and mood disorders

RB Mansur, E Brietzke, RS McIntyre - Neuroscience & Biobehavioral …, 2015 - Elsevier
Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies
have highlighted the public health relevance of this association, insofar as both conditions …

Is there a bi-directional relationship between depression and obesity among adult men and women? Systematic review and bias-adjusted meta analysis

M Mannan, A Mamun, S Doi, A Clavarino - Asian journal of psychiatry, 2016 - Elsevier
The rapidly increasing prevalence of both obesity and depression represent two major
public health concerns worldwide. But the evidence regarding the direction and strength of …

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

JRI Coleman, WJ Peyrot, KL Purves, KAS Davis… - Molecular …, 2020 - nature.com
Depression is more frequent among individuals exposed to traumatic events. Both trauma
exposure and depression are heritable. However, the relationship between these traits …

The impact of pre-pregnancy BMI on maternal depressive and anxiety symptoms during pregnancy and the postpartum period: A systematic review and meta-analysis

BA Dachew, G Ayano, K Betts, R Alati - Journal of Affective Disorders, 2021 - Elsevier
Background Studies have reported conflicting results on the association between maternal
pre-pregnancy weight and adverse mental health outcomes during pregnancy and the …

Shared genetic loci between body mass index and major psychiatric disorders: a genome-wide association study

S Bahrami, NE Steen, A Shadrin, K O'Connell… - JAMA …, 2020 - jamanetwork.com
Importance People with major psychiatric disorders (MPDs) have a 10-to 20-year shorter life
span than the rest of the population, and this difference is mainly due to comorbid …

[HTML][HTML] The potential of polygenic risk scores to predict antidepressant treatment response in major depression: a systematic review

JJ Meerman, SE Ter Hark, JGE Janzing… - Journal of Affective …, 2022 - Elsevier
Background Understanding the genetic underpinnings of antidepressant treatment response
in unipolar major depressive disorder (MDD) can be useful in identifying patients at risk for …

The combined effects of obesity, abdominal obesity and major depression/anxiety on health-related quality of life: the lifelines cohort study

YT Nigatu, SA Reijneveld, P de Jonge, E van Rossum… - PloS one, 2016 - journals.plos.org
Background Obesity and major depressive disorder (MDD)/anxiety disorders often co-occur
and aggravate each other resulting in adverse health-related outcomes. As little is known …