In trypanosomes, RNA polymerase II transcription is polycistronic and individual mRNAs are
excised by trans-splicing and polyadenylation. The lack of individual gene transcription …

All organisms adapt to changes in their environment by adjustments in gene expression,
and in all organisms, from Escherichia coli to man, the most important control point is at …

Through the analysis of hundreds of full-length cDNAs from fifteen species representing all
major orders of dinoflagellates, we demonstrate that nuclear-encoded mRNAs in all species …

In trypanosomes, all RNAs are processed by the concerted action of trans-splicing and
polyadenylation. In trans-splicing, a common spliced leader (SL) is donated to all mRNAs …

In eukaryotes, RNA polymerase (pol) I exclusively transcribes the large rRNA gene unit
(rDNA) and mRNA is synthesized by RNA pol II. The African trypanosome, Trypanosoma …

The parasites Leishmania spp., Trypanosoma brucei, and Trypanosoma cruzi are the
trypanosomatid protozoa that cause the deadly human diseases leishmaniasis, African …

Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 52900 Israel mRNA maturation in
trypanosomes differs from the process in most eukaryotes mainly because protein-coding …

Transcription in the kinetoplastid protozoa shows substantial variation from the paradigms of
eukaryotic gene expression, including polycistronic transcription, a paucity of RNA …

Genome projects involving Leishmania and other trypanosomatids have revealed that most
genes in these organisms are organized into large clusters of genes on the same DNA …

Typical general transcription factors, such as TATA binding protein and TFII B, have not yet
been identified in any member of the Trypanosomatidae family of parasitic protozoa …