Coumarins and coumarin-related compounds in pharmacotherapy of cancer
Cancer is one of the most common causes of disease-related deaths worldwide. Despite the
discovery of many chemotherapeutic drugs that inhibit uncontrolled cell division processes …
discovery of many chemotherapeutic drugs that inhibit uncontrolled cell division processes …
Therapeutic effects of coumarins with different substitution patterns
The use of derivatives of natural and synthetic origin has gained attention because of their
therapeutic effects against human diseases. Coumarins are one of the most common …
therapeutic effects against human diseases. Coumarins are one of the most common …
Coumarins as antioxidants
Coumarins, a well-known class of naturally occurring compounds, display a remarkable
array of biochemical and pharmacological actions, some of which suggest that certain …
array of biochemical and pharmacological actions, some of which suggest that certain …
Coumarins: old compounds with novel promising therapeutic perspectives
ME Riveiro, N De Kimpe, A Moglioni… - Current medicinal …, 2010 - ingentaconnect.com
Natural as well as synthetic coumarins have recently drawn much attention due to its broad
pharmacological activities. Many coumarins and their derivatives exert anti-coagulant, anti …
pharmacological activities. Many coumarins and their derivatives exert anti-coagulant, anti …
Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis, and carcinogenesis
Oxidative stress can be defined as the imbalance between cellular oxidant species
production and antioxidant capability. Reactive oxygen species (ROS) are involved in a …
production and antioxidant capability. Reactive oxygen species (ROS) are involved in a …
The structure and pharmacological functions of coumarins and their derivatives
L Wu, X Wang, W Xu, F Farzaneh… - Current medicinal …, 2009 - ingentaconnect.com
Coumarins are of many different structures. They constitute an important class of
pharmacological agents possessing a range of different physiological activities including …
pharmacological agents possessing a range of different physiological activities including …
Pharmacological and nutritional effects of natural coumarins and their structure–activity relationships
JJ Zhu, JG Jiang - Molecular nutrition & food research, 2018 - Wiley Online Library
Coumarins are fused benzene and pyrone ring systems with a wide spectrum of
bioactivities, including antitumor, anti‐inflammation, antiviral, and antibacterial effects. In this …
bioactivities, including antitumor, anti‐inflammation, antiviral, and antibacterial effects. In this …
Coumarin: a promising scaffold for anticancer agents
M Kaur, S Kohli, S Sandhu, Y Bansal… - Anti-Cancer Agents in …, 2015 - ingentaconnect.com
Coumarin enjoys an important place in drug discovery process due to its presence in
diversity of biologically active compounds. Many compounds of plant origin are derivatives …
diversity of biologically active compounds. Many compounds of plant origin are derivatives …
The anticancer properties of dietary polyphenols and its relation with apoptosis
Aberrantly regulated apoptosis is involved in the pathogenesis of several diseases and
defective apoptosis leads to uncontrolled cell proliferation and tumorigenesis. Cancer is an …
defective apoptosis leads to uncontrolled cell proliferation and tumorigenesis. Cancer is an …
Coumarins scaffolds as COX inhibitors
The discovery of COX enzymes has led to a better understanding of inflammation and its
related biological pathways. Apart from being related to inflammation and pain, it has also …
related biological pathways. Apart from being related to inflammation and pain, it has also …