Steroids in teleost fishes: A functional point of view

J Tokarz, G Möller, MH de Angelis, J Adamski - Steroids, 2015 - Elsevier
Steroid hormones are involved in the regulation of a variety of processes like embryonic
development, sex differentiation, metabolism, immune responses, circadian rhythms, stress …

Glucocorticoid receptor β (GRβ): beyond its dominant-negative function

P Ramos-Ramírez, O Tliba - International Journal of Molecular Sciences, 2021 - mdpi.com
Glucocorticoids (GCs) act via the GC receptor (GR), a receptor ubiquitously expressed in the
body where it drives a broad spectrum of responses within distinct cell types and tissues …

Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

PA Watson, YF Chen, MD Balbas… - Proceedings of the …, 2010 - National Acad Sciences
Androgen receptor (AR) splice variants lacking the ligand binding domain (ARVs), originally
isolated from prostate cancer cell lines derived from a single patient, are detected in normal …

Human glucocorticoid receptor isoform β: recent understanding of its potential implications in physiology and pathophysiology

T Kino, YA Su, GP Chrousos - Cellular and Molecular Life Sciences, 2009 - Springer
The human glucocorticoid receptor (GR) gene expresses two splicing isoforms α and β
through alternative use of specific exons 9α and 9β. In contrast to the classic receptor GRα …

PPARγΔ5, a naturally occurring dominant-negative splice isoform, impairs PPARγ function and adipocyte differentiation

M Aprile, S Cataldi, MR Ambrosio, V D'Esposito, K Lim… - Cell reports, 2018 - cell.com
Peroxisome-proliferator-activated receptor γ (PPARγ) regulates glucose and lipid
homeostasis, insulin signaling, and adipocyte differentiation. Here, we report the skip** of …

Corticosteroid receptors in the brain: transcriptional mechanisms for specificity and context-dependent effects

OC Meijer, JC Buurstede, MJM Schaaf - Cellular and molecular …, 2019 - Springer
Corticosteroid hormones act in the brain to support adaptation to stress via binding to
mineralocorticoid and glucocorticoid receptors (MR and GR). These receptors act in large …

Pathogenesis of malaria-associated acute respiratory distress syndrome

PE Van den Steen, K Deroost, J Deckers… - Trends in …, 2013 - cell.com
Malaria-associated acute respiratory distress syndrome (MA-ARDS) is an increasingly
reported, often lethal, and incompletely understood complication of malaria. We discuss and …

Zebrafish and steroids: what do we know and what do we need to know?

J Tokarz, G Möller, MH de Angelis, J Adamski - The Journal of steroid …, 2013 - Elsevier
Zebrafish, Danio rerio, has long been used as a model organism in developmental biology.
Nowadays, due to their advantages compared to other model animals, the fish gain …

The nuclear receptor 4A family members: mediators in human disease and autophagy

L Chen, F Fan, L Wu, Y Zhao - Cellular & molecular biology letters, 2020 - Springer
Abstract The Nuclear receptor 4A (NR4A) subfamily, which belongs to the nuclear receptor
(NR) superfamily, has three members: NR4A1 (Nur77), NR4A2 (Nurr1) and NR4A3 (Nor1) …

Discovery of glucocorticoid receptor-β in mice with a role in metabolism

TD Hinds Jr, S Ramakrishnan, HA Cash… - Molecular …, 2010 - academic.oup.com
Glucocorticoid hormones control diverse physiological processes, including metabolism and
immunity, by activating the major glucocorticoid receptor (GR) isoform, GRα. However …