Deiodinases and their intricate role in thyroid hormone homeostasis

C Luongo, M Dentice, D Salvatore - Nature Reviews Endocrinology, 2019 - nature.com
The deiodinase family of enzymes mediates the activation and inactivation of thyroid
hormone. The role of these enzymes in the regulation of the systemic concentrations of …

Furosemide as a functional marker of acute kidney injury in ICU patients: a new role for an old drug

F Mariano, A Mella, M Vincenti, L Biancone - Journal of nephrology, 2019 - Springer
New pharmacokinetics insight suggests that the furosemide pharmacology occurring in ICU
patients with AKI is similar, but not equal to that described in chronic stable renal patients …

Flexible and integrated dual carbon sensor for multiplexed detection of nonylphenol and paroxetine in tap water samples

NO Gomes, CD Mendonça, SAS Machado… - Microchimica Acta, 2021 - Springer
Multiplex detection of emerging pollutants is essential to improve quality control of water
treatment plants, which requires portable systems capable of real-time monitoring. In this …

Phototransformation study of the antidepressant paroxetine in surface waters

T Gornik, L Carena, T Kosjek, D Vione - Science of the Total Environment, 2021 - Elsevier
In this work, the photochemistry of the antidepressant paroxetine (PXT) and its
photochemical fate in surface waters were investigated. The direct photolysis quantum yield …

Genetic factors and symptom dimensions associated with antidepressant treatment outcomes: clues for new potential therapeutic targets?

A Martone, C Possidente, G Fanelli, C Fabbri… - European Archives of …, 2024 - Springer
Abstract Treatment response and resistance in major depressive disorder (MDD) show a
significant genetic component, but previous studies had limited power also due to MDD …

Spatial variation in the detection rates of frequently studied pharmaceuticals in Asian, European and North American rivers

Y Jameel, D Valle, P Kay - Science of The Total Environment, 2020 - Elsevier
Pharmaceutical consumption has expanded rapidly during the last century and their
persistent presence in the environment has become a major concern. Unfortunately, our …

Solar light–driven photocatalytic degradation and mineralization of beta blockers propranolol and atenolol by carbon dot/TiO2 composite

A Ponkshe, P Thakur - Environmental Science and Pollution Research, 2022 - Springer
Herein improved solar light–driven photocatalytic degradation and mineralization of two
emerging pollutants as well as recalcitrant beta blockers propranolol (PR) and atenolol (AT) …

Ultraviolet photolysis of four typical cardiovascular drugs: mechanisms, influencing factors, degradation pathways, and toxicity trends

S **, W Lin, A Liu, Z Gao, H Lin, Y Ren - Environmental Science and …, 2021 - Springer
The cardiovascular drugs (CDDs), such as metoprolol (MET), atenolol (ATE), bezafibrate
(BZB), and atorvastatin (ATO), have been frequently detected in the water environment. They …

Developmental fluoxetine exposure affects adolescent and adult bone depending on the dose and period of exposure in mice

HP Fricke, CJ Krajco, MJ Perry… - Physiological …, 2023 - Wiley Online Library
At the end of gestation, fetal skeleton rapidly accumulates calcium, and bone development
continues in offspring postnatally. To accommodate, maternal skeletal physiology is …

Prescription drugs and mitochondrial metabolism

CA Schmidt - Bioscience Reports, 2022 - portlandpress.com
Mitochondria are central to the physiology and survival of nearly all eukaryotic cells and
house diverse metabolic processes including oxidative phosphorylation, reactive oxygen …