Biointerface design for vertical nanoprobes

R Elnathan, MG Barbato, X Guo, A Mariano… - Nature Reviews …, 2022 - nature.com
Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

[HTML][HTML] Long-acting transdermal drug delivery formulations: Current developments and innovative pharmaceutical approaches

T Karve, A Dandekar, V Agrahari, MM Peet… - Advanced Drug Delivery …, 2024 - Elsevier
Transdermal administration remains an active research and development area as an
alternative route for long-acting drug delivery. It avoids major drawbacks of conventional oral …

[HTML][HTML] Wearable patches for transdermal drug delivery

J He, Y Zhang, X Yu, C Xu - Acta pharmaceutica sinica B, 2023 - Elsevier
Transdermal drug delivery systems (TDDs) avoid gastrointestinal degradation and hepatic
first-pass metabolism, providing good drug bioavailability and patient compliance. One …

Microreactor-based micro/nanomaterials: Fabrication, advances, and outlook

J Ran, X Wang, Y Liu, S Yin, S Li, L Zhang - Materials Horizons, 2023 - pubs.rsc.org
Micro/nanomaterials are widely used in optoelectronics, environmental materials,
bioimaging, agricultural industries, and drug delivery owing to their marvelous features, such …

Engineering Efficient CAR‐T Cells via Electroactive Nanoinjection

AR Shokouhi, Y Chen, HZ Yoh, J Brenker… - Advanced …, 2023 - Wiley Online Library
Chimeric antigen receptor (CAR)‐T cell therapy has emerged as a promising cell‐based
immunotherapy approach for treating blood disorders and cancers, but genetically …

[HTML][HTML] Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery

T Ahmed - Biosensors and Bioelectronics: X, 2022 - Elsevier
The core of the drug research and screening processes is predicting the effect of drugs prior
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …

Tiny titans-unravelling the potential of polysaccharides and proteins based dissolving microneedles in drug delivery and theranostics: a comprehensive review

M Kenchegowda, U Hani, A Al Fatease… - International Journal of …, 2023 - Elsevier
In recent years, microneedles (MNs) have emerged as a promising alternative to traditional
drug delivery systems in transdermal drug delivery. The use of MNs has demonstrated …

Biomimetic microneedles: Exploring the recent advances on a microfabricated system for precision delivery of drugs, peptides, and proteins

CE Umeyor, V Shelke, A Pol, P Kolekar… - Future Journal of …, 2023 - Springer
Background Despite its popularity, acceptability, and convenience, the oral route is not the
classical route for the administration of all critical bioactives including lipophilic drugs …

High‐Precision Synthesis of RNA‐Loaded Lipid Nanoparticles for Biomedical Applications

H Seo, L Jeon, J Kwon, H Lee - Advanced Healthcare …, 2023 - Wiley Online Library
The recent development of RNA‐based therapeutics in delivering nucleic acids for gene
editing and regulating protein translation has led to the effective treatment of various …

Electroactive nanoinjection platform for intracellular delivery and gene silencing

AR Shokouhi, Y Chen, HZ Yoh, T Murayama… - Journal of …, 2023 - Springer
Background Nanoinjection—the process of intracellular delivery using vertically configured
nanostructures—is a physical route that efficiently negotiates the plasma membrane, with …