Sepsis is defined as organ dysfunction resulting from the host's deleterious response to
infection. One of the most common organs affected is the kidneys, resulting in sepsis …

Acute pancreatitis is one of the most common GI conditions requiring acute hospitalisation
and has a rising incidence. In recent years, important insights on the management of acute …

Background Whether the use of balanced multielectrolyte solution (BMES) in preference to
0.9% sodium chloride solution (saline) in critically ill patients reduces the risk of acute kidney …

Importance Intravenous fluids are used for almost all intensive care unit (ICU) patients.
Clinical and laboratory studies have questioned whether specific fluid types result in …

Background Both balanced crystalloids and saline are used for intravenous fluid
administration in critically ill adults, but it is not known which results in better clinical …

Background Comparative clinical effects of balanced crystalloids and saline are uncertain,
particularly in noncritically ill patients cared for outside an intensive care unit (ICU). Methods …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Perioperative organ injury is among the leading causes of morbidity and mortality of surgical
patients. Among different types of perioperative organ injury, acute kidney injury occurs …

Importance Saline (0.9% sodium chloride) is the most commonly administered intravenous
fluid; however, its use may be associated with acute kidney injury (AKI) and increased …

Aggressive fluid resuscitation to achieve a central venous pressure (CVP) greater than 8 mm
Hg has been promoted as the standard of care, in the management of patients with severe …