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Mycobacterium tuberculosis EsxL induces TNF-α secretion through activation of TLR2 dependent MAPK and NF-κB pathways
Mycobacterium tuberculosis (Mtb) employs distinct strategies to circumvent host immune
responses during the infection process. Various Mtb cell-wall associated and secretory …
responses during the infection process. Various Mtb cell-wall associated and secretory …
[HTML][HTML] IL-36γ promotes killing of Mycobacterium tuberculosis by macrophages via WNT5A-induced noncanonical WNT signaling
Mycobacterium tuberculosis, which primarily infects mononuclear phagocytes, remains the
leading bacterial cause of enormous morbidity and mortality because of bacterial infections …
leading bacterial cause of enormous morbidity and mortality because of bacterial infections …
Early secreted antigenic target of 6 kda-like proteins of Mycobacterium tuberculosis: diagnostic and vaccine relevance
AS Mustafa - The International Journal of Mycobacteriology, 2022 - journals.lww.com
Background: Early secreted antigenic target of 6 kDa (ESAT6) is low-molecular-weight and
immunodominant protein of Mycobacterium tuberculosis with relevance to diagnosis and …
immunodominant protein of Mycobacterium tuberculosis with relevance to diagnosis and …
[HTML][HTML] Mycobacterium tuberculosis EsxL inhibits MHC-II expression by promoting hypermethylation in class-II transactivator loci in macrophages
Mycobacterium tuberculosis is known to modulate the host immune responses to facilitate its
persistence inside the host cells. One of the key mechanisms includes repression of class-II …
persistence inside the host cells. One of the key mechanisms includes repression of class-II …
Insight about cell wall remodulation triggered by rifampicin in Mycobacterium tuberculosis
JE Meneguello, GS Arita, JV de Oliveira Silva… - Tuberculosis, 2020 - Elsevier
Rifampicin plays an important role during the treatment of tuberculosis, which makes it to be
recommended throughout the regimen. The molecular target for rifampicin activity and …
recommended throughout the regimen. The molecular target for rifampicin activity and …
Biophysical and immunological characterization of the ESX-4 system ESAT-6 family proteins Rv3444c and Rv3445c from Mycobacterium tuberculosis H37Rv
The ESAT-6 family proteins of Mycobacterium tuberculosis are regarded as the key
mediators in mycobacterial virulence and are largely considered as antigens that can …
mediators in mycobacterial virulence and are largely considered as antigens that can …
Immunological characterization of chimeras of high specificity antigens from Mycobacterium tuberculosis H37Rv
Tuberculosis remains a serious global health problem. BCG is the only prophylactic TB
vaccine and it shows variable protective efficacy. Chimeric protein subunit vaccines hold …
vaccine and it shows variable protective efficacy. Chimeric protein subunit vaccines hold …
[SITAT][C] Secretory Proteins from Mycobacterium tuberculosis and their Conjecture for Companion Diagnostics
S Sainalabdeen, A Narain - National Medicos Organisation Journal (एन एम ओ …, 2018