Horizontal gene transfer and adaptive evolution in bacteria

BJ Arnold, IT Huang, WP Hanage - Nature Reviews Microbiology, 2022 - nature.com
Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …

Horizontal gene transfer of antibiotic resistance genes in biofilms

C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …

Antimicrobial resistance in ESKAPE pathogens

DMP De Oliveira, BM Forde, TJ Kidd… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …

Conjugative plasmids interact with insertion sequences to shape the horizontal transfer of antimicrobial resistance genes

Y Che, Y Yang, X Xu, K Břinda… - Proceedings of the …, 2021 - National Acad Sciences
It is well established that plasmids play an important role in the dissemination of
antimicrobial resistance (AMR) genes; however, little is known about the role of the …

Mobile genetic element flexibility as an underlying principle to bacterial evolution

AJ Weisberg, JH Chang - Annual Review of Microbiology, 2023 - annualreviews.org
Mobile genetic elements are key to the evolution of bacteria and traits that affect host and
ecosystem health. Here, we use a framework of a hierarchical and modular system that …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

ICEberg 2.0: an updated database of bacterial integrative and conjugative elements

M Liu, X Li, Y **e, D Bi, J Sun, J Li, C Tai… - Nucleic acids …, 2019 - academic.oup.com
Abstract ICEberg 2.0 (http://db-mml. sjtu. edu. cn/ICEberg/) is an updated database that
provides comprehensive information about bacterial integrative and conjugative elements …

Phage-plasmids promote recombination and emergence of phages and plasmids

E Pfeifer, EPC Rocha - Nature Communications, 2024 - nature.com
Phages and plasmids are regarded as distinct types of mobile genetic elements that drive
bacterial evolution by horizontal gene transfer. However, the distinction between both types …

Evolution of plasmid mobility: origin and fate of conjugative and nonconjugative plasmids

C Coluzzi, MP Garcillán-Barcia… - Molecular Biology …, 2022 - academic.oup.com
Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …

Integrative and conjugative elements (ICEs): what they do and how they work

CM Johnson, AD Grossman - Annual review of genetics, 2015 - annualreviews.org
Horizontal gene transfer plays a major role in microbial evolution, allowing microbes to
acquire new genes and phenotypes. Integrative and conjugative elements (ICEs, aka …