Computation through neural population dynamics

S Vyas, MD Golub, D Sussillo… - Annual review of …, 2020 - annualreviews.org
Significant experimental, computational, and theoretical work has identified rich structure
within the coordinated activity of interconnected neural populations. An emerging challenge …

If deep learning is the answer, what is the question?

A Saxe, S Nelli, C Summerfield - Nature Reviews Neuroscience, 2021 - nature.com
Neuroscience research is undergoing a minor revolution. Recent advances in machine
learning and artificial intelligence research have opened up new ways of thinking about …

Orthogonal representations for robust context-dependent task performance in brains and neural networks

T Flesch, K Juechems, T Dumbalska, A Saxe… - Neuron, 2022 - cell.com
How do neural populations code for multiple, potentially conflicting tasks? Here we used
computational simulations involving neural networks to define" lazy" and" rich" coding …

Single-trial neural dynamics are dominated by richly varied movements

S Musall, MT Kaufman, AL Juavinett, S Gluf… - Nature …, 2019 - nature.com
When experts are immersed in a task, do their brains prioritize task-related activity? Most
efforts to understand neural activity during well-learned tasks focus on cognitive …

Task representations in neural networks trained to perform many cognitive tasks

GR Yang, MR Joglekar, HF Song, WT Newsome… - Nature …, 2019 - nature.com
The brain has the ability to flexibly perform many tasks, but the underlying mechanism
cannot be elucidated in traditional experimental and modeling studies designed for one task …

The population doctrine in cognitive neuroscience

RB Ebitz, BY Hayden - Neuron, 2021 - cell.com
A major shift is happening within neurophysiology: a population doctrine is drawing level
with the single-neuron doctrine that has long dominated the field. Population-level ideas …

Neural manifolds for the control of movement

JA Gallego, MG Perich, LE Miller, SA Solla - Neuron, 2017 - cell.com
The analysis of neural dynamics in several brain cortices has consistently uncovered low-
dimensional manifolds that capture a significant fraction of neural variability. These neural …

Towards the neural population doctrine

S Saxena, JP Cunningham - Current opinion in neurobiology, 2019 - Elsevier
Highlights•New generations of recording and computing technologies have enabled
neuroscience at the level of the neural population.•Landmark scientific findings suggest the …

The geometry of abstraction in the hippocampus and prefrontal cortex

S Bernardi, MK Benna, M Rigotti, J Munuera, S Fusi… - Cell, 2020 - cell.com
The curse of dimensionality plagues models of reinforcement learning and decision making.
The process of abstraction solves this by constructing variables describing features shared …

Why neurons mix: high dimensionality for higher cognition

S Fusi, EK Miller, M Rigotti - Current opinion in neurobiology, 2016 - Elsevier
Neurons often respond to diverse combinations of task-relevant variables. This form of
mixed selectivity plays an important computational role which is related to the dimensionality …