A review on structural mechanisms of protein-persistent organic pollutant (POP) interactions

N Nagar, H Saxena, A Pathak, A Mishra, KM Poluri - Chemosphere, 2023 - Elsevier
With the advent of the industrial revolution, the accumulation of persistent organic pollutants
(POPs) in the environment has become ubiquitous. POPs are halogen-containing organic …

Effect of enterohepatic circulation on the accumulation of per-and polyfluoroalkyl substances: evidence from experimental and computational studies

H Cao, Z Zhou, Z Hu, C Wei, J Li, L Wang… - Environmental …, 2022 - ACS Publications
The pharmacokinetic characteristics of per-and polyfluoroalkyl substances (PFAS) affect
their distribution and bioaccumulation in biological systems. The enterohepatic circulation …

Molecular interactions between bovine serum albumin (BSA) and trihalophenol: Insights from spectroscopic, calorimetric and molecular modeling studies

W Liang, Z Zhang, Q Zhu, Z Han, C Huang… - … Acta Part A: Molecular …, 2023 - Elsevier
The issue of disinfection byproducts (DBPs) in the water has received critical attention due to
the health effects on humans. In the water environment, interactions between bovine serum …

Antioxidant defence system is responsible for the toxicological interactions of mixtures: A case study on PFOS and PFOA in Daphnia magna

HB Yang, YZ Zhao, Y Tang, HQ Gong, F Guo… - Science of the Total …, 2019 - Elsevier
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are two types of
perfluorinated compounds (PFCs) frequently studied in recent years due to their potential for …

[HTML][HTML] The current state of amyloidosis therapeutics and the potential role of fluorine in their treatment

M Dabur, JA Loureiro, MC Pereira - Biochimie, 2022 - Elsevier
Amyloidosis, commonly known as amyloid-associated diseases, is characterized by
improperly folded proteins accumulating in tissues and eventually causing organ damage …

Screening of potential PFOS alternatives to decrease liver bioaccumulation: experimental and computational approaches

H Cao, Z Zhou, L Wang, G Liu, Y Sun… - … science & technology, 2019 - ACS Publications
Perfluorooctanesulfonate (PFOS) is a persistent organic pollutant with significant
bioaccumulation potential in liver tissues. Exposure to PFOS could cause increase of liver …

Emerging Polar Phenolic Disinfection Byproducts Are High-Affinity Human Transthyretin Disruptors: An in Vitro and in Silico Study

X Yang, W Ou, Y **, J Chen, H Liu - Environmental Science & …, 2019 - ACS Publications
Phenolic disinfection byproducts (phenolic-DBPs) have been identified in recent years.
However, the toxicity data for phenolic-DBPs are scarce, hampering their risk assessment …

[HTML][HTML] Insights into toxicity of polychlorinated naphthalenes to multiple human endocrine receptors: Mechanism and health risk analysis

X Li, W Gu, B Zhang, X **n, Q Kang, M Yang… - Environment …, 2022 - Elsevier
This study explored the combined disruption mechanism of polychlorinated naphthalenes
(PCNs) on the three key receptors (estrogen receptor, thyroid receptor, and adrenoceptor) of …

Integration of computational toxicology, toxicogenomics data mining, and omics techniques to unveil toxicity pathways

X Wang, F Li, J Chen, C Ji, H Wu - ACS Sustainable Chemistry & …, 2021 - ACS Publications
Growing numbers of synthetic chemicals have potential endocrine-disrupting effects and
cause potential ecological and health risks. However, the primary toxicity pathways and …

Identification of hydrocarbon sulfonates as previously overlooked transthyretin ligands in the environment

Y Gong, J Sun, X Wang, H Barrett… - Environmental Science & …, 2024 - ACS Publications
Incidences of thyroid disease, which has long been hypothesized to be partially caused by
exposure to thyroid hormone disrupting chemicals (TDCs), have rapidly increased in recent …