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A review on structural mechanisms of protein-persistent organic pollutant (POP) interactions
With the advent of the industrial revolution, the accumulation of persistent organic pollutants
(POPs) in the environment has become ubiquitous. POPs are halogen-containing organic …
(POPs) in the environment has become ubiquitous. POPs are halogen-containing organic …
Effect of enterohepatic circulation on the accumulation of per-and polyfluoroalkyl substances: evidence from experimental and computational studies
H Cao, Z Zhou, Z Hu, C Wei, J Li, L Wang… - Environmental …, 2022 - ACS Publications
The pharmacokinetic characteristics of per-and polyfluoroalkyl substances (PFAS) affect
their distribution and bioaccumulation in biological systems. The enterohepatic circulation …
their distribution and bioaccumulation in biological systems. The enterohepatic circulation …
Molecular interactions between bovine serum albumin (BSA) and trihalophenol: Insights from spectroscopic, calorimetric and molecular modeling studies
W Liang, Z Zhang, Q Zhu, Z Han, C Huang… - … Acta Part A: Molecular …, 2023 - Elsevier
The issue of disinfection byproducts (DBPs) in the water has received critical attention due to
the health effects on humans. In the water environment, interactions between bovine serum …
the health effects on humans. In the water environment, interactions between bovine serum …
Antioxidant defence system is responsible for the toxicological interactions of mixtures: A case study on PFOS and PFOA in Daphnia magna
HB Yang, YZ Zhao, Y Tang, HQ Gong, F Guo… - Science of the Total …, 2019 - Elsevier
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are two types of
perfluorinated compounds (PFCs) frequently studied in recent years due to their potential for …
perfluorinated compounds (PFCs) frequently studied in recent years due to their potential for …
[HTML][HTML] The current state of amyloidosis therapeutics and the potential role of fluorine in their treatment
Amyloidosis, commonly known as amyloid-associated diseases, is characterized by
improperly folded proteins accumulating in tissues and eventually causing organ damage …
improperly folded proteins accumulating in tissues and eventually causing organ damage …
Screening of potential PFOS alternatives to decrease liver bioaccumulation: experimental and computational approaches
H Cao, Z Zhou, L Wang, G Liu, Y Sun… - … science & technology, 2019 - ACS Publications
Perfluorooctanesulfonate (PFOS) is a persistent organic pollutant with significant
bioaccumulation potential in liver tissues. Exposure to PFOS could cause increase of liver …
bioaccumulation potential in liver tissues. Exposure to PFOS could cause increase of liver …
Emerging Polar Phenolic Disinfection Byproducts Are High-Affinity Human Transthyretin Disruptors: An in Vitro and in Silico Study
X Yang, W Ou, Y **, J Chen, H Liu - Environmental Science & …, 2019 - ACS Publications
Phenolic disinfection byproducts (phenolic-DBPs) have been identified in recent years.
However, the toxicity data for phenolic-DBPs are scarce, hampering their risk assessment …
However, the toxicity data for phenolic-DBPs are scarce, hampering their risk assessment …
[HTML][HTML] Insights into toxicity of polychlorinated naphthalenes to multiple human endocrine receptors: Mechanism and health risk analysis
This study explored the combined disruption mechanism of polychlorinated naphthalenes
(PCNs) on the three key receptors (estrogen receptor, thyroid receptor, and adrenoceptor) of …
(PCNs) on the three key receptors (estrogen receptor, thyroid receptor, and adrenoceptor) of …
Integration of computational toxicology, toxicogenomics data mining, and omics techniques to unveil toxicity pathways
Growing numbers of synthetic chemicals have potential endocrine-disrupting effects and
cause potential ecological and health risks. However, the primary toxicity pathways and …
cause potential ecological and health risks. However, the primary toxicity pathways and …
Identification of hydrocarbon sulfonates as previously overlooked transthyretin ligands in the environment
Y Gong, J Sun, X Wang, H Barrett… - Environmental Science & …, 2024 - ACS Publications
Incidences of thyroid disease, which has long been hypothesized to be partially caused by
exposure to thyroid hormone disrupting chemicals (TDCs), have rapidly increased in recent …
exposure to thyroid hormone disrupting chemicals (TDCs), have rapidly increased in recent …