Regenerative medicine for equine musculoskeletal diseases

I Ribitsch, GL Oreff, F Jenner - Animals, 2021 - mdpi.com
Simple Summary Lameness due to musculoskeletal disease is the most common diagnosis
in equine veterinary practice. Many of these orthopaedic disorders are chronic problems, for …

A comparative review of autologous conditioned serum and autologous protein solution for treatment of osteoarthritis in horses

L Camargo Garbin, MJ Morris - Frontiers in Veterinary Science, 2021 - frontiersin.org
Many alternative treatments aimed at modulating osteoarthritis (OA) progression have been
developed in the past decades, including the use of cytokine inhibitors. IL-1β is considered …

Equine autologous conditioned serum and autologous protein solution

KF Ortved - Veterinary Clinics: Equine Practice, 2023 - vetequine.theclinics.com
Musculoskeletal injuries involving joints, tendons, and ligaments occur commonly in the
horse, especially in those performing in athletic pursuits. Such injuries present challenges …

A systematic review and meta‐analysis of the efficacy of platelet‐rich plasma products for treatment of equine joint disease

C Peng, L Yang, R Labens, Y Gao… - Equine Veterinary …, 2024 - Wiley Online Library
Background Equine joint disease including septic arthritis (SA) and osteoarthritis (OA) is a
critical cause of equine lameness. Platelet‐rich plasma (PRP) is one of the most popular …

Autologous conditioned serum in equine and human orthopedic therapy: A systematic review

PKA Tokawa, PM Brossi, RYA Baccarin - Research in Veterinary Science, 2022 - Elsevier
This systematic review aims to compile and present information of studies evaluating the
effectiveness of autologous conditioned serum (ACS) in the healing of tendon, ligament and …

In vitro anti-inflammatory and regenerative effects of autologous conditioned serum from dogs with osteoarthritis

S Soontararak, P Ardaum, N Senarat, S Yangtara… - Animals, 2022 - mdpi.com
Simple Summary Autologous conditioned serum (ACS) has benefits in managing
osteoarthritis (OA) due to enriched mediators, including Interleukin-1 receptor antagonists …

[HTML][HTML] Platelet-Rich Plasma and Related Orthobiologics for the Treatment of Equine Musculoskeletal Disorders—A Bibliometric Analysis from 2000 to 2024

JU Carmona, LH Carmona-Ramírez, C López - Veterinary Sciences, 2024 - mdpi.com
Simple Summary Platelet-rich plasma and related orthobiologics, such as platelet lysates,
autologous conditioned serums, and autologous protein solutions, are relatively new …

Conditioned serum in vitro treatment of chondrocyte pellets and osteoarthritic explants

M Löfgren, S Ekman, J Ekholm… - Equine veterinary …, 2023 - Wiley Online Library
Background Autologous conditioned serum (ACS) is used to treat osteoarthritis in horses,
although its effects are not fully investigated. Objectives To investigate the effects of equine …

Synovium secretome as a disease-modifying treatment for equine osteoarthritis

SM Hernandez, L Begum, LE Keller… - American Journal of …, 2022 - Am Vet Med Assoc
OBJECTIVE To identify chondroprotective factors as potential disease-modifying
osteoarthritis treatments using an unbiased, bottom-up proteomics approach. SAMPLES …

Potential Mechanism of Action of Current Point-of-Care Autologous Therapy Treatments for Osteoarthritis of the Knee—A Narrative Review

J Woodell-May, K Steckbeck, W King - International Journal of Molecular …, 2021 - mdpi.com
Osteoarthritis (OA) is a progressive degenerative disease that manifests as pain and
inflammation and often results in total joint replacement. There is significant interest in …