The role of insufficient sleep and circadian misalignment in obesity

JP Chaput, AW McHill, RC Cox, JL Broussard… - Nature Reviews …, 2023 - nature.com
Traditional risk factors for obesity and the metabolic syndrome, such as excess energy
intake and lack of physical activity, cannot fully explain the high prevalence of these …

Sex differences in sleep, circadian rhythms, and metabolism: implications for precision medicine

R Lok, J Qian, SL Chellappa - Sleep medicine reviews, 2024 - Elsevier
The number of individuals experiencing sleep loss has exponentially risen over the past
decades. Extrapolation of laboratory findings to the real world suggests that females are …

[HTML][HTML] Sleep loss can cause death through accumulation of reactive oxygen species in the gut

A Vaccaro, YK Dor, K Nambara, EA Pollina, C Lin… - Cell, 2020 - cell.com
The view that sleep is essential for survival is supported by the ubiquity of this behavior, the
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …

The translational neuroscience of sleep: a contextual framework

MA Grandner, FX Fernandez - Science, 2021 - science.org
Sleep is entwined across many physiologic processes in the brain and periphery, thereby
exerting tremendous influence on our well-being. Yet sleep exists in a social-environmental …

The sleep-deprived human brain

AJ Krause, EB Simon, BA Mander, SM Greer… - Nature Reviews …, 2017 - nature.com
How does a lack of sleep affect our brains? In contrast to the benefits of sleep, frameworks
exploring the impact of sleep loss are relatively lacking. Importantly, the effects of sleep …

Sleep duration and quality: impact on lifestyle behaviors and cardiometabolic health: a scientific statement from the American Heart Association

MP St-Onge, MA Grandner, D Brown, MB Conroy… - Circulation, 2016 - ahajournals.org
Sleep is increasingly recognized as an important lifestyle contributor to health. However, this
has not always been the case, and an increasing number of Americans choose to curtail …

Sleep influences on obesity, insulin resistance, and risk of type 2 diabetes

S Reutrakul, E Van Cauter - Metabolism, 2018 - Elsevier
A large body of epidemiologic evidence has linked insufficient sleep duration and quality to
the risk of obesity, insulin resistance and type 2 diabetes. To address putative causal …

Hypothalamic syndrome

HL Müller, M Tauber, EA Lawson, J Özyurt… - Nature reviews Disease …, 2022 - nature.com
Hypothalamic syndrome (HS) is a rare disorder caused by disease-related and/or treatment-
related injury to the hypothalamus, most commonly associated with rare, non-cancerous …

Sleep loss and the socio-emotional brain

EB Simon, R Vallat, CM Barnes, MP Walker - Trends in cognitive sciences, 2020 - cell.com
Are you feeling emotionally fragile, moody, unpredictable, even ungenerous to those around
you? Here, we review how and why these phenomena can occur as a result of insufficient …

Sleep deprivation: effects on weight loss and weight loss maintenance

E Papatriantafyllou, D Efthymiou, E Zoumbaneas… - Nutrients, 2022 - mdpi.com
This narrative review presents the findings from intervention studies on the effects of sleep
deprivation on eating habits, metabolic rate, and the hormones regulating metabolism, and …