Natural products (NPs) have a long history as sources for drug discovery, more than half of
approved drugs are related to NPs, which also exhibit multifaceted advantages in the clinical …

Pyrrole is a heterocyclic structure with diverse pharmacophores, enabling the creation of an
extensive lead molecule library. Its broad range of pharmacological profiles has concerned …

Within the intricate fabric of human physiology, cholesterol, a lipid present in cell
membranes exerts a discernible effect on the concentration of the drug in human body that …

Several previous research indicate that treating Mesembryanthemum crystallinum may aid
in reducing adipogenesis and triacylglycerol level and improving hyperglycemia and …

Seven new indole-diterpenoids, penpaxilloids A–E (1–5), 7-methoxypaxilline-13-ene (6),
and 10-hydroxy-paspaline (7), along with 20 known ones (8–27), were isolated from the …

The biological activities of natural products (NPs) provided precious resources for the
development of new drugs. Numerous studies have shown that statins exhibit cytotoxic …

Cinnamon is one of the world's oldest and most popular spices, and is derived from the inner
bark of several tree species from the genus Cinnamomum. During the last two decades …

Fifteen sesquiterpenoids, including five previously undescribed monomers with oxidative
rearranged skeletons (sarglabenoids A–E, 1–5) and three previously unreported lindenane …

Fungi have been identified as a prolific source of structurally unique secondary metabolites,
many of which display promising biological and pharmacological properties. This review …

Abstract (±)-Hypernumqulins A–H (1–8), eight pairs of enantiomeric quinoline alkaloids
fused with an isopentenyl and a germacrane-type sesquiterpenoid, featuring an …