Synthetic heterocyclic candidates as promising α-glucosidase inhibitors: An overview

M Dhameja, P Gupta - European journal of medicinal chemistry, 2019 - Elsevier
Abstract α-Glucosidase enzyme inhibition is an effective therapeutic decorum in the
treatment of type 2 diabetes mellitus. Since 1990, three α-glucosidase inhibitors are known …

Multicomponent reactions as a potent tool for the synthesis of benzodiazepines

H Farhid, V Khodkari, MT Nazeri… - Organic & …, 2021 - pubs.rsc.org
Benzodiazepines (BZDs), a diverse class of benzofused seven-membered N-heterocycles,
display essential pharmacological properties and play vital roles in some biochemical …

Immobilized nickel boride nanoparticles on magnetic functionalized multi-walled carbon nanotubes: a new nanocomposite for the efficient one-pot synthesis of 1, 4 …

FM Aminzadeh, B Zeynizadeh - Nanoscale Advances, 2023 - pubs.rsc.org
In this study, a new magnetic nanocomposite consisting of Ni2B nanoparticles anchored on
magnetic functionalized multi-walled carbon nanotubes (Fe3O4/f-MWCNT/Ni2B) was …

Multicomponent DNA-compatible synthesis of an annelated benzodiazepine scaffold for focused chemical libraries

G Zhao, H Wang, J Luo, X He, F **ong, Y Li… - Organic …, 2023 - ACS Publications
Annelated benzodiazepines are attractive drug-like scaffolds with a broad spectrum of
biological activities. Incorporation of this heterocyclic core into DNA-encoded chemical …

Synthesis of functionalized chromene and spirochromenes using l-proline-melamine as highly efficient and recyclable homogeneous catalyst at room temperature

S Nagaraju, B Paplal, K Sathish, S Giri, D Kashinath - Tetrahedron letters, 2017 - Elsevier
An efficient and recyclable homogeneous catalyst is developed using commercially cheap l-
proline and melamine for the synthesis of chromenes and spirochromenes (spirooxindoles) …

Bio-fabrication of silver-silver chloride nanoparticles using Annona muricata leaf extract: characterization, biological, dye degradation and eco-toxicity studies

A Velidandi, NPP Pabbathi, S Dahariya… - International Journal of …, 2022 - Springer
This work reports the bio-fabrication of silver-silver chloride nanoparticles by using aqueous
Annona muricata leaf extract. Using UV–visible spectrophotometer, the presence of …

A facile and efficient multicomponent ultrasound-assisted “on water” synthesis of benzodiazepine ring

SK Maury, D Kumar, A Kamal, HK Singh, S Kumari… - Molecular …, 2021 - Springer
A facile and efficient multicomponent synthesis of benzodiazepine ring in water under
ultrasound irradiation is reported first time. The current procedure escapes traditional …

Naphthoquinone fused diazepines targeting hyperamylasemia: potential therapeutic agents for diabetes and cancer

S Chahal, P Rani, R Singh, G Joshi… - Future Medicinal …, 2024 - Taylor & Francis
Aim: Elevated levels of amylase in the blood, known as hyperamylasemia, have been
correlated with diabetes and cancer. To investigate the impact of hyperamylasemia on …

Sulfonic acid functionalized covalent organic frameworks as efficient catalyst for the one-pot tandem reactions

K Gong, C Li, D Zhang, H Lu, Y Wang, H Li, H Zhang - Molecular Catalysis, 2022 - Elsevier
A covalent organic framework containing hydroxyl groups (HO-COF) has been predesigned
and synthesized by the cyclotrimerization reaction of acetyls, which was used as a pre …

Synthesis of 2-styryl-quinazoline and 3-styryl-quinoxaline based sulfonate esters via sp 3 C–H activation and their evaluation for α-glucosidase inhibition

N Satyanarayana, BR Sree, K Sathish… - New Journal of …, 2022 - pubs.rsc.org
Synthesis of 2-styryl-quinazolines and 3-styryl-quinoxaline based sulfonates is reported via
sp3 C–H functionalization in the presence of triethylamine (10 mol%). The resulting …