Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-
malarial drugs used for chemoprevention is perennially threatened by drug resistance. This …

Antimalarial drug resistance, in particular resistance to Plasmodium falciparum, challenges
the treatment and control of malaria. In this Review, we summarise evolving patterns of …

One hundred and twenty-five million women in malaria-endemic areas become pregnant
each year (see Dellicour et al. PLoS Med 7: e1000221 [2010]) and require protection from …

Background Every year, more than 32 million pregnancies in sub-Saharan Africa are at risk
of malaria infection and its adverse consequences. The effectiveness of the intermittent …

Malaria remains one of the most preventable causes of adverse birth outcomes. Intermittent
preventive treatment in pregnancy (IPTp) with sulfadoxine–pyrimethamine is used to prevent …

Background Seasonal malaria chemoprevention is used in 13 countries in the Sahel region
of Africa to prevent malaria in children younger than 5 years. Resistance of Plasmodium …

Background CRISPR-based diagnostics are a new class of highly sensitive and specific
assays with multiple applications in infectious disease diagnosis. SHERLOCK, or Specific …

Summary Background Resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine
threatens the antimalarial effectiveness of intermittent preventive treatment during …

Background. Owing to increasing sulfadoxine-pyrimethamine (SP) resistance in sub-
Saharan Africa, monitoring the effectiveness of intermittent preventive therapy in pregnancy …

Background 2· 6 million stillbirths occur annually worldwide. The association between
malaria in pregnancy and stillbirth has yet to be comprehensively quantified. We aimed to …