The diagnosis of brain metastasis (BrM) has historically been a dooming diagnosis that is
nothing less than a death sentence, with few treatment options for palliation or prolonging …

Despite major therapeutic advances in the management of patients with breast cancer,
central nervous system (CNS) metastases remain an intractable problem, particularly in …

Chemotherapy has made substantial progress in the therapy of systemic cancer, but the
phar-macological efficacy is insufficient in the treatment of brain metastases. Fractionated …

The metastasis of cancer to the central nervous system (CNS) remains a devastating clinical
reality, carrying an estimated survival time of less than one year in spite of recent therapeutic …

Breast cancer is a common cause of brain metastases, with metastases occurring in at least
10–16% of patients. Longer survival of patients with metastatic breast cancer and the use of …

Purpose Brain metastases are a common sequelae of breast cancer. Survival varies widely
based on diagnosis-specific prognostic factors (PF). We previously published a prognostic …

One of the most feared sequelae after a diagnosis of advanced breast cancer is
development of metastases to the brain as this diagnosis can affect physical function …

Purpose To provide formal expert consensus–based recommendations to practicing
oncologists and others on the management of brain metastases for patients with human …

To define prognostic factors for breast cancer patients with brain metastases, compare their
clinical courses and prognoses according to breast cancer subtypes, and analyze the …

Brain metastasis is an end stage in breast cancer progression. Traditional treatment options
have minimal efficacy, and overall survival is on the order of months. The incidence of brain …