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Regulatory mechanism of MicroRNA expression in cancer
Z Ali Syeda, SSS Langden, C Munkhzul, M Lee… - International journal of …, 2020 - mdpi.com
Altered gene expression is the primary molecular mechanism responsible for the
pathological processes of human diseases, including cancer. MicroRNAs (miRNAs) are …
pathological processes of human diseases, including cancer. MicroRNAs (miRNAs) are …
MicroRNA let-7 and viral infections: focus on mechanisms of action
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …
cellular processes, a number of which are involved in host defense mechanisms. In …
DIANA-miTED: a microRNA tissue expression database
Abstract microRNAs (miRNAs) are short (∼ 23nt) single-stranded non-coding RNAs that act
as potent post-transcriptional gene expression regulators. Information about miRNA …
as potent post-transcriptional gene expression regulators. Information about miRNA …
miRmine: a database of human miRNA expression profiles
Motivation MicroRNAs (miRNAs) are small non-coding RNAs that are involved in post-
transcriptional regulation of gene expression. In this high-throughput sequencing era, a …
transcriptional regulation of gene expression. In this high-throughput sequencing era, a …
A microRNA-inducible CRISPR–Cas9 platform serves as a microRNA sensor and cell-type-specific genome regulation tool
XW Wang, LF Hu, J Hao, LQ Liao, YT Chiu, M Shi… - Nature cell …, 2019 - nature.com
Abstract microRNAs (miRNAs) are small noncoding RNAs that play important regulatory
roles in plants, animals and viruses. Measuring miRNA activity in vivo remains a big …
roles in plants, animals and viruses. Measuring miRNA activity in vivo remains a big …
Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers
RNA editing, a widespread post-transcriptional mechanism, has emerged as a new player in
cancer biology. Recent studies have reported key roles for individual miRNA editing events …
cancer biology. Recent studies have reported key roles for individual miRNA editing events …
ADAR2/miR-589-3p axis controls glioblastoma cell migration/invasion
V Cesarini, DA Silvestris, V Tassinari… - Nucleic acids …, 2018 - academic.oup.com
Recent studies have reported the emerging role of microRNAs (miRNAs) in human cancers.
We systematically characterized miRNA expression and editing in the human brain, which …
We systematically characterized miRNA expression and editing in the human brain, which …
Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets
Abstract A-to-I RNA editing is an important post-transcriptional modification, known to be
altered in tumors. It targets dozens of sites within miRNAs, some of which impact miRNA …
altered in tumors. It targets dozens of sites within miRNAs, some of which impact miRNA …
An update of miRNASNP database for better SNP selection by GWAS data, miRNA expression and online tools
MicroRNAs (miRNAs) are key regulators of gene expression involved in a broad range of
biological processes. MiRNASNP aims to provide single nucleotide polymorphisms (SNPs) …
biological processes. MiRNASNP aims to provide single nucleotide polymorphisms (SNPs) …
Epigenetic regulation of human non-coding RNA gene transcription
Recent investigations on the non-protein-coding transcriptome of human cells have
revealed previously hidden layers of gene regulation relying on regulatory non-protein …
revealed previously hidden layers of gene regulation relying on regulatory non-protein …