Fibroblast growth factors (FGFs) make up a large family of polypeptide growth factors that
are found in organisms ranging from nematodes to humans. In vertebrates, the 22 members …

Cell signaling plays a key role in the development of all multicellular organisms. Numerous
studies have established the importance of Hedgehog signaling in a wide variety of …

The zebrafish has become one of the most important model organisms to study biologial
processes in vivo. As a vertebrate that has many of the strengths of invertebrate model …

The neural crest is a multipotent, migratory cell population that is unique to vertebrate
embryos and gives rise to many derivatives, ranging from the peripheral nervous system to …

Fibroblast growth factors (FGFs) have been implicated in diverse cellular processes
including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and …

Fluorescence correlation spectroscopy (FCS) is a powerful technique to measure
concentrations, mobilities, and interactions of fluorescent biomolecules. It can be applied to …

Fibroblast growth factors (FGF) are secreted molecules which function through the activation
of specific tyrosine kinases receptors, the FGF receptors that transduce the signal by …

Neurogenesis in the develo** central nervous system consists of the induction and
proliferation of neural progenitor cells and their subsequent differentiation into mature …

Fibroblast growth factor (FGF) signalling has been implicated during several phases of early
embryogenesis, including the patterning of the embryonic axes, the induction and/or …

Two organizing centres operate at long-range distances within the anterior neural plate to
pattern the forebrain, midbrain and hindbrain. Important progress has been made in …