[HTML][HTML] Highly attenuated poxvirus-based vaccines against emerging viral diseases

B Perdiguero, P Pérez, L Marcos-Villar… - Journal of molecular …, 2023‏ - Elsevier
Although one member of the poxvirus family, variola virus, has caused one of the most
devastating human infections worldwide, smallpox, the knowledge gained over the last 30 …

Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals

M Hubert, F Guivel-Benhassine, T Bruel, F Porrot… - Cell Host & Microbe, 2023‏ - cell.com
Mpox virus (MPXV) caused a multi-country outbreak in non-endemic areas in 2022.
Following historic success of smallpox vaccination with vaccinia virus (VACV)-based …

Glycan masking of a non-neutralising epitope enhances neutralising antibodies targeting the RBD of SARS-CoV-2 and its variants

GW Carnell, M Billmeier, S Vishwanath… - Frontiers in …, 2023‏ - frontiersin.org
The accelerated development of the first generation COVID-19 vaccines has saved millions
of lives, and potentially more from the long-term sequelae of SARS-CoV-2 infection. The …

[HTML][HTML] Viral-vectored boosting of OmcB-or CPAF-specific T-cell responses fail to enhance protection from Chlamydia muridarum in infection-immune mice and elicits …

TB Poston, J Girardi, AG Polson, A Bhardwaj… - Mucosal …, 2024‏ - Elsevier
A vaccine is needed to combat the Chlamydia epidemic. Replication-deficient viral vectors
are safe and induce antigen-specific T-cell memory. We tested the ability of intramuscular …

[HTML][HTML] Rendezvous with Vaccinia Virus in the Post-smallpox Era: R&D Advances

Y Wang - Viruses, 2023‏ - mdpi.com
Smallpox was eradicated in less than 200 years after Edward Jenner's practice of cowpox
variolation in 1796. The forty-three years of us living free of smallpox, beginning in 1979 …

Characterization and comparison of immunity against MPXV for individuals infected with MPXV or vaccinated with modified vaccinia Ankara vaccines

A Wiedemann, M Surénaud, M Hubert… - The Journal of …, 2025‏ - academic.oup.com
The 2022 Mpox virus (MPXV) outbreak revitalized questions about immunity against MPXV
and vaccinia-based vaccines (VAC-V), but studies are limited. We analyzed immunity …

Managing bacterial sexually transmitted infections (STIs) and preventing HIV/STIs in Europe

C Bébéar, S Pereyre, B Berçot… - The Lancet Regional …, 2023‏ - thelancet.com
HIV, viral hepatitis, and other sexually transmitted infections (STIs) are major public health
threats worldwide, and the WHO European Region is no exception. The WHO estimates that …

T-Cell Immunity in COVID-19-Recovered Individuals and Individuals Vaccinated with the Combined Vector Vaccine Gam-COVID-Vac

SP Krechetov, VV Vtorushina, EV Inviyaeva… - International Journal of …, 2023‏ - mdpi.com
The COVID-19 pandemic has required extensive research on the new coronavirus SARS-
CoV-2 and the creation of new highly effective vaccines. The presence of T-cells in the body …

[PDF][PDF] Statistical methods for leveraging high-dimensional data from high-throughput measurements in vaccine clinical development

BP Hejblum - 2024‏ - hal.science
6 Directions for future research 71 6.1 Multi-modal data integration to enhance
measurement resolution. 71 6.2 Incorporating prior biological knowledge to enhance results …