Refactoring transcription factors for metabolic engineering

C Deng, Y Wu, X Lv, J Li, Y Liu, G Du, J Chen… - Biotechnology …, 2022 - Elsevier
Due to the ability to regulate target metabolic pathways globally and dynamically, metabolic
regulation systems composed of transcription factors have been widely used in metabolic …

A post-genomic view of the ecophysiology, catabolism and biotechnological relevance of sulphate-reducing prokaryotes

R Rabus, SS Venceslau, L Wöhlbrand… - Advances in microbial …, 2015 - Elsevier
Dissimilatory sulphate reduction is the unifying and defining trait of sulphate-reducing
prokaryotes (SRP). In their predominant habitats, sulphate-rich marine sediments, SRP have …

RegulonDB v12.0: a comprehensive resource of transcriptional regulation in E. coli K-12

H Salgado, S Gama-Castro, P Lara… - Nucleic Acids …, 2024 - academic.oup.com
RegulonDB is a database that contains the most comprehensive corpus of knowledge of the
regulation of transcription initiation of Escherichia coli K-12, including data from both …

Disentangling direct from indirect relationships in association networks

N **ao, A Zhou, ML Kempher, BY Zhou, ZJ Shi… - Proceedings of the …, 2022 - pnas.org
Networks are vital tools for understanding and modeling interactions in complex systems in
science and engineering, and direct and indirect interactions are pervasive in all types of …

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

JL Gehrig, S Venkatesh, HW Chang, MC Hibberd… - Science, 2019 - science.org
INTRODUCTION There is a dimension to postnatal human development that involves
assembly of microbial communities in different body habitats, including the gut. Children with …

Microbial interactions shape cheese flavour formation

C Melkonian, F Zorrilla, I Kjærbølling, S Blasche… - Nature …, 2023 - nature.com
Cheese fermentation and flavour formation are the result of complex biochemical reactions
driven by the activity of multiple microorganisms. Here, we studied the roles of microbial …

Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children

LV Blanton, MR Charbonneau, T Salih, MJ Barratt… - Science, 2016 - science.org
INTRODUCTION As we come to appreciate how our microbial communities (microbiota)
assemble following birth, there is an opportunity to determine how this facet of our …

Simultaneous generation of many RNA-seq libraries in a single reaction

AA Shishkin, G Giannoukos, A Kucukural, D Ciulla… - Nature …, 2015 - nature.com
Although RNA-seq is a powerful tool, the considerable time and cost associated with library
construction has limited its utilization for various applications. RNAtag-Seq, an approach to …

Micronutrient requirements and sharing capabilities of the human gut microbiome

DA Rodionov, AA Arzamasov, MS Khoroshkin… - Frontiers in …, 2019 - frontiersin.org
The human gut microbiome harbors a diverse array of metabolic pathways contributing to its
development and homeostasis via a complex web of diet-dependent metabolic interactions …

Transcription factor-based biosensors in biotechnology: current state and future prospects

R Mahr, J Frunzke - Applied microbiology and biotechnology, 2016 - Springer
Living organisms have evolved a plethora of sensing systems for the intra-and extracellular
detection of small molecules, ions or physical parameters. Several recent studies have …