Genomic analysis of many nonmodel species has uncovered an incredible diversity of sex
chromosome systems, making it possible to empirically test the rich body of evolutionary …

Animal sex chromosomes typically carry the upstream sex-determining gene that triggers
testis or ovary development and, in some species, are regulated by global dosage …

Long-read sequencing is driving rapid progress in genome assembly across all major
groups of life, including species of the family Drosophilidae, a longtime model system for …

The canonical model of sex-chromosome evolution predicts that, as recombination is
suppressed along sex chromosomes, gametologs will progressively differentiate, eventually …

Although sex is a fundamental component of eukaryotic reproduction, the genetic systems
that control sex determination are highly variable. In many organisms the presence of sex …

Antimicrobial peptides are host-encoded immune effectors that combat pathogens and
shape the microbiome in plants and animals. However, little is known about how the host …

Sex chromosomes can evolve once recombination is halted between a homologous pair of
chromosomes. Owing to detailed studies using key model systems, we have a nuanced …

Contrary to classic theory prediction, sex-chromosome homomorphy is prevalent in the
animal kingdom but it is unclear how ancient homomorphic sex chromosomes avoid …

Modulation of nutrient digestion and absorption is one of the post-ingestion mechanisms that
guarantees the best exploitation of food resources, even when they are nutritionally poor or …

Understanding phylogenetic relationships among taxa is key to designing and implementing
comparative analyses. The genus Drosophila, which contains over 1600 species, is one of …