Abstract Type 2 diabetes (T2D) is a multifactorial disease with substantial genetic risk, for
which the underlying biological mechanisms are not fully understood. In this study, we …

Insulin resistance (IR) is a well-established risk factor for metabolic disease. The ratio of
triglycerides to high-density lipoprotein cholesterol (TG: HDL-C) is a surrogate marker of IR …

The way by which subcutaneous adipose tissue (SAT) expands and undergoes remodeling
by storing excess lipids through expansion of adipocytes (hypertrophy) or recruitment of new …

Obesity is a major risk factor for cardiometabolic diseases. Nevertheless, a substantial
proportion of individuals with obesity do not suffer cardiometabolic comorbidities. The …

Recent large-scale genomic association studies found evidence for a genetic link between
increased risk of type 2 diabetes and decreased risk for adiposity-related traits, reminiscent …

Abstract Type 2 diabetes (T2D) is highly prevalent and is a strong contributor for
cardiovascular disease. However, there is significant heterogeneity in disease pathogenesis …

Caffeic acid (CA) and chlorogenic acid (CGA) are phenolic compounds claimed to be
responsible for the metabolic effects of coffee and tea consumption. Along with their …

BACKGROUND: Dyslipoproteinemia often involves simultaneous derangements of multiple
lipid traits. We aimed to evaluate the phenotypic and genetic characteristics of combined …

Long-chain acyl-CoA synthetase 1 (ACSL1) plays an important role in fatty acid metabolism
and fat deposition. The transcription of the ACSL1 gene is regulated specifically among cells …

Proteomics is a key analytical method in meat research thanks to its potential in investigating
the proteins at interplay in post-mortem muscles. This study aimed to characterize for the first …