The Latin word lupus, meaning wolf, was in the medical literature prior to the 1200s to
describe skin lesions that devour flesh, and the resources available to physicians to help …

Protein-bound uremic toxins (PBUTs) are associated with the progression of chronic kidney
disease (CKD) and its associated morbidity and mortality. The conventional dialysis …

Introduction: Fast food is a major risk factor for atherosclerosis, a leading cause of morbidity
and mortality in the Western world. Apelin, the endogenous adipokine, can protect against …

Introduction Indoxyl sulfate (IS), a protein-bound uremic toxin, is associated with kidney
function and chronic kidney disease (CKD)-related complications. Currently, serum IS levels …

This article illustrates how dietary flaxseed can be used to reduce cancer risk, specifically by
attenuating obesity, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD). We …

Introduction: Type 2 diabetes is a significant health concern in the 21st century, and its
prevalence continues to rise despite efforts to promote preventive lifestyle changes. This …

Flaxseed oil (FO) has displayed potential anti-diabetes properties by providing a high
content of α-linolenic acid. However, the effects and mechanisms of FO on type 1 diabetes …

Renal fibrosis is the common and final pathological process of kidney diseases. As a
dynamic and reversible post-translational modification, SUMOylation and deSUMOylation of …

ABSTRACT A diet supplemented with cholic acid (CA), the primary 12α-hydroxylated bile
acid, can induce hepatic lipid accumulation in rats without obesity. This study examined the …

Gut microbiota plays a pivotal role in various health challenges, particularly in mitigating
diabetes-induced renal damage. Numerous studies have highlighted that modifying gut …