The phosphonic acid functional group, which is characterized by a phosphorus atom
bonded to three oxygen atoms (two hydroxy groups and one P= O double bond) and one …

Nucleoside triphosphates (NTPs and dNTPs, Figure 1) have important therapeutic and
diagnostic applications. Experience with syntheses of these compounds, and discussions …

A century after their discovery, phosphonates have become important compounds
recognized both for their use as efficient reagents in organic synthesis and for their …

Osteomyelitis is a major problem worldwide and is devastating due to the potential for limb-
threatening sequelae and mortality. Osteomyelitis pathogens are bone-attached biofilms …

The palladium-catalyzed cross-coupling of dialkylphosphite with aromatic electrophiles
(Hirao coupling) was re-investigated. Some limitations in terms of palladium loadings and …

Organophosphorus acids (phosphoric, phosphonic, and phosphinic) and their derivatives
(salts, esters) are highly promising coupling molecules that allow the anchoring of organic …

Inhibitors of the zinc protease neutral endopeptidase (NEP, EC 3.4. 24.11) offer significant
therapeutic interest as antihypertensives due to their ability to potentiate the biological action …

Inhibitors of the protease from human immunodeficiency virus 1 (HIV-1) were designed,
synthesized, and kinetically characterized. Analogues of a heptapeptide substrate of HIV-1 …

The surfaces of alumina particles were modified by grafting with phenylphosphonic acid and
its organic-soluble ester derivatives (diethyl phenylphosphonate and bis (trimethylsilyl) …

In the bioinspired repair process of tooth enamel, it is important to simultaneously mimic the
organic-matrix-induced biomineralization and increase the binding strength at the …