Redox processes are at the heart of synthetic methods that rely on either electrochemistry or
photoredox catalysis, but how do electrochemistry and photoredox catalysis compare? Both …

Numerous light-based diagnostic and therapeutic devices are routinely used in the clinic.
These devices have a familiar look as items plugged in the wall or placed at patients' …

Generalist methods for cellular segmentation have good out-of-the-box performance on a
variety of image types; however, existing methods struggle for images that are degraded by …

A fundamental challenge in fluorescence microscopy is the photon shot noise arising from
the inevitable stochasticity of photon detection. Noise increases measurement uncertainty …

Induced pluripotent stem cell (iPSC)-derived organoids provide models to study human
organ development. Single-cell transcriptomics enable highly resolved descriptions of cell …

When used appropriately, a confocal fluorescence microscope is an excellent tool for
making quantitative measurements in cells and tissues. The confocal microscope's ability to …

The proliferation of microscopy methods for live-cell imaging offers many new possibilities
for users but can also be challenging to navigate. The prevailing challenge in live-cell …

Long-term subcellular intravital imaging in mammals is vital to study diverse intercellular
behaviors and organelle functions during native physiological processes. However, optical …

Capturing mitochondria's intricate and dynamic structure poses a daunting challenge for
optical nanoscopy. Different labeling strategies have been demonstrated for live-cell …

Autophagy is a cellular process with important functions that drive neurodegenerative
diseases and cancers. Lysosomal hyperacidification is a hallmark of autophagy. Lysosomal …