Polyester based polymeric nano and microparticles for pharmaceutical purposes: A review on formulation approaches

F Molavi, M Barzegar-Jalali, H Hamishehkar - Journal of Controlled …, 2020 - Elsevier
The novel polymeric particulate systems show high potential in their clinical effectiveness.
Nevertheless, many of the drug delivery systems developed in the research laboratories …

Advanced progress of microencapsulation technologies: In vivo and in vitro models for studying oral and transdermal drug deliveries

PL Lam, R Gambari - Journal of Controlled Release, 2014 - Elsevier
This review provides an overall discussion of microencapsulation systems for both oral and
transdermal drug deliveries. Clinically, many drugs, especially proteins and peptides, are …

Engineered PLGA nano-and micro-carriers for pulmonary delivery: challenges and promises

F Ungaro, I d'Angelo, A Miro… - Journal of Pharmacy …, 2012 - academic.oup.com
Objectives The aim of this review is to summarize the current state-of-the-art in poly (lactic-co-
glycolic acid)(PLGA) carriers for inhalation. It presents the rational of use, the potential and …

Oral insulin delivery: Barriers, strategies, and formulation approaches: A comprehensive review

SS Shetty, P Halagali, AP Johnson… - International Journal of …, 2023 - Elsevier
Diabetes Mellitus is characterized by a hyperglycemic condition which can either be caused
by the destruction of the beta cells or by the resistance developed against insulin in the cells …

[HTML][HTML] Classification of scanning electron microscope images of pharmaceutical excipients using deep convolutional neural networks with transfer learning

H Iwata, Y Hayashi, A Hasegawa, K Terayama… - International Journal of …, 2022 - Elsevier
Abstract Convolutional Neural Networks (CNNs) are image analysis techniques that have
been applied to image classification in various fields. In this study, we applied a CNN to …

A rapid-acting, long-acting insulin formulation based on a phospholipid complex loaded PHBHHx nanoparticles

Q Peng, ZR Zhang, T Gong, GQ Chen, X Sun - Biomaterials, 2012 - Elsevier
The application of poly (hydroxybutyrate-co-hydroxyhexanoate)(PHBHHx) for sustained and
controlled delivery of hydrophilic insulin was made possible by preparing insulin …

Powder production and particle engineering for dry powder inhaler formulations

YW Lin, J Wong, L Qu, HK Chan… - Current pharmaceutical …, 2015 - benthamdirect.com
Dry powder inhalers have become increasingly attractive for pulmonary delivery of locally
and systemically effective medications. In comparison to the liquid counterparts, such as …

Alternative carriers in dry powder inhaler formulations

Y Rahimpour, M Kouhsoltani, H Hamishehkar - Drug discovery today, 2014 - Elsevier
Highlights•Applications of alternative carriers to lactose in DPIs are reviewed.•Lactose, the
most commonly used carrier in DPI formulations, has some limitations.•These limitations …

Effect of carrier particle shape on dry powder inhaler performance

W Kaialy, A Alhalaweh, SP Velaga… - International journal of …, 2011 - Elsevier
The aim of this study was to characterise the aerosolisation properties of salbutamol
sulphate (SS) from dry powder inhaler (DPI) formulations containing different carrier …

A quantitative approach to predicting lung deposition profiles of pharmaceutical powder aerosols

S Yaqoubi, HK Chan, A Nokhodchi… - International Journal of …, 2021 - Elsevier
Dry powder inhalers (DPI) are widely used systems for pulmonary delivery of therapeutics.
The inhalation performance of DPIs is influenced by formulation features, inhaler device and …