Neurogenesis in aging and age-related neurodegenerative diseases

L Culig, X Chu, VA Bohr - Ageing research reviews, 2022 - Elsevier
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

Current understanding of Alzheimer's disease diagnosis and treatment

J Weller, A Budson - F1000Research, 2018 - pmc.ncbi.nlm.nih.gov
Alzheimer's disease is the most common cause of dementia worldwide, with the prevalence
continuing to grow in part because of the aging world population. This neurodegenerative …

Imaging techniques in Alzheimer's disease: a review of applications in early diagnosis and longitudinal monitoring

WM van Oostveen, ECM de Lange - International journal of molecular …, 2021 - mdpi.com
Background. Alzheimer's disease (AD) is a progressive neurodegenerative disorder
affecting many individuals worldwide with no effective treatment to date. AD is characterized …

Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer's Disease

O Hansson, S Lehmann, M Otto, H Zetterberg… - Alzheimer's research & …, 2019 - Springer
The cerebrospinal fluid (CSF) biochemical markers (biomarkers) Amyloidβ 42 (Aβ 42), total
Tau (T-tau) and Tau phosphorylated at threonine 181 (P-tau 181) have proven diagnostic …

The continuum of aging and age-related diseases: common mechanisms but different rates

C Franceschi, P Garagnani, C Morsiani, M Conte… - Frontiers in …, 2018 - frontiersin.org
Geroscience, the new interdisciplinary field that aims to understand the relationship between
aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on …

Current state of Alzheimer's fluid biomarkers

JL Molinuevo, S Ayton, R Batrla, MM Bednar… - Acta …, 2018 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease with a complex and
heterogeneous pathophysiology. The number of people living with AD is predicted to …

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease

MR Brier, B Gordon, K Friedrichsen… - Science translational …, 2016 - science.org
Alzheimer's disease (AD) is characterized by two molecular pathologies: cerebral β-
amyloidosis in the form of β-amyloid (Aβ) plaques and tauopathy in the form of neurofibrillary …

Automatic detection of Alzheimer's disease progression: An efficient information fusion approach with heterogeneous ensemble classifiers

S El-Sappagh, F Ali, T Abuhmed, J Singh, JM Alonso - Neurocomputing, 2022 - Elsevier
Predicting Alzheimer's disease (AD) progression is crucial for improving the management of
this chronic disease. Usually, data from AD patients are multimodal and time series in …

[HTML][HTML] Linking the amyloid, tau, and mitochondrial hypotheses of Alzheimer's disease and identifying promising drug targets

Z Fišar - Biomolecules, 2022 - mdpi.com
Damage or loss of brain cells and impaired neurochemistry, neurogenesis, and synaptic and
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …

[HTML][HTML] The impact of gamma transcranial alternating current stimulation (tACS) on cognitive and memory processes in patients with mild cognitive impairment or …

NR Nissim, DVH Pham, T Poddar, E Blutt, RH Hamilton - Brain stimulation, 2023 - Elsevier
Background Transcranial alternating current stimulation (tACS)—a noninvasive brain
stimulation technique that modulates cortical oscillations through entrainment—has been …