Nanoparticle preparation of pharmaceutical compounds via wet milling: Current status and future prospects

R Kumar, AK Thakur, P Chaudhari, RK Arya… - Powder Technology, 2024 - Elsevier
This review discusses the preparation of nanoparticles/nanosuspensions using wet milling
processes. It explores wet milling techniques, such as oscillatory bead milling, planetary …

[HTML][HTML] Updates on the conversion of nanosuspensions to solid oral dosage forms

A Tsiaxerli, E Vardaka, C Moutroupidis… - Journal of Food and …, 2024 - pmc.ncbi.nlm.nih.gov
Pharmaceutical nanosuspensions, also called nanocrystals, are heterogeneous mainly
aqueous dispersions of insoluble drug particles stabilised by surfactants and/or polymers …

[HTML][HTML] Formulation and optimization of transferrin-modified genistein nanocrystals: In vitro anti-cancer assessment and pharmacokinetic evaluation

FM Iqbal, C Rodríguez-Nogales, N Boulens… - International Journal of …, 2024 - Elsevier
In this research work, nanocrystals (NC) of poorly water-soluble drug genistein (Gen) were
formulated to improve its aqueous solubility and bioavailability. Genistein nanocrystals (Gen …

A comparative study on in vitro and in vivo characteristics of enzalutamide nanocrystals versus amorphous solid dispersions and a better prediction for bioavailability …

X Guo, Y Guo, M Zhang, B Yang, H Liu, T Yin… - International Journal of …, 2022 - Elsevier
This study systematically compared enzalutamide (ENZ) nanocrystals and amorphous
formulation (Xtandi® Tablets) and proposed an effective method for predicting …

Design and Bottom-up Production of an Aerosolizable Cannabidiol Nanosuspension

L Casula, M Schlich, MC Cardia, E Lai… - Molecular …, 2024 - ACS Publications
Cannabidiol (CBD), a small nonpsychoactive molecule derived from Cannabis sativa, exerts
a variety of therapeutic actions, such as anti-inflammatory, antioxidant, and antibacterial …

Different Size Formulations of Fluopyram: Preparation, Antifungal Activity, and Accumulation in the Fungal Pathogen Botrytis cinerea

Y Wang, S Zhang, Y Xu, H Li, R Zhang, D Chen, J Xu… - Molecules, 2023 - mdpi.com
Nanotechnology is revolutionizing the efficient production and sustainable development of
modern agriculture. Understanding the pesticide activity of both nano-and conventional …

[HTML][HTML] Nanosuspension Innovations: Expanding Horizons in Drug Delivery Techniques

S Jacob, FS Kather, SHS Boddu, M Attimarad, AB Nair - Pharmaceutics, 2025 - mdpi.com
Nanosuspensions (NS), with their submicron particle sizes and unique physicochemical
properties, provide a versatile solution for enhancing the administration of medications that …

[HTML][HTML] Navigating translational research in nanomedicine: A strategic guide to formulation and manufacturing

X Zhang, HW Chan, Z Shao, Q Wang, S Chow… - International Journal of …, 2025 - Elsevier
Over the past two decades, extensive research has focused on both the fundamental and
applied aspects of nanomedicine, driven by the compelling advantages that nanoparticles …

Development of Dermal Lidocaine Nanosuspension Formulation by the Wet Milling Method Using Experimental Design: In Vitro/In Vivo Evaluation

O Kral, S Ilbasmis-Tamer, S Han, F Tirnaksiz - ACS omega, 2024 - ACS Publications
Lidocaine (LID), frequently used in dermal applications, is a nonpolar local anesthetic agent
that is practically insoluble in water. The main aim of this study is to develop the …

Nanocrystal formulations of mebendazole employing quality by design and molecular level insights by atomistic simulations

E Vardaka, K Kachrimanis - Drug Development and Industrial …, 2024 - Taylor & Francis
Objective The present study investigates the production of mebendazole nanocrystal
formulations by wet media milling. Significance Nanocrystal formulations are expected to …