Nanoparticle preparation of pharmaceutical compounds via wet milling: Current status and future prospects
This review discusses the preparation of nanoparticles/nanosuspensions using wet milling
processes. It explores wet milling techniques, such as oscillatory bead milling, planetary …
processes. It explores wet milling techniques, such as oscillatory bead milling, planetary …
[HTML][HTML] Updates on the conversion of nanosuspensions to solid oral dosage forms
A Tsiaxerli, E Vardaka, C Moutroupidis… - Journal of Food and …, 2024 - pmc.ncbi.nlm.nih.gov
Pharmaceutical nanosuspensions, also called nanocrystals, are heterogeneous mainly
aqueous dispersions of insoluble drug particles stabilised by surfactants and/or polymers …
aqueous dispersions of insoluble drug particles stabilised by surfactants and/or polymers …
[HTML][HTML] Formulation and optimization of transferrin-modified genistein nanocrystals: In vitro anti-cancer assessment and pharmacokinetic evaluation
FM Iqbal, C Rodríguez-Nogales, N Boulens… - International Journal of …, 2024 - Elsevier
In this research work, nanocrystals (NC) of poorly water-soluble drug genistein (Gen) were
formulated to improve its aqueous solubility and bioavailability. Genistein nanocrystals (Gen …
formulated to improve its aqueous solubility and bioavailability. Genistein nanocrystals (Gen …
A comparative study on in vitro and in vivo characteristics of enzalutamide nanocrystals versus amorphous solid dispersions and a better prediction for bioavailability …
X Guo, Y Guo, M Zhang, B Yang, H Liu, T Yin… - International Journal of …, 2022 - Elsevier
This study systematically compared enzalutamide (ENZ) nanocrystals and amorphous
formulation (Xtandi® Tablets) and proposed an effective method for predicting …
formulation (Xtandi® Tablets) and proposed an effective method for predicting …
Design and Bottom-up Production of an Aerosolizable Cannabidiol Nanosuspension
Cannabidiol (CBD), a small nonpsychoactive molecule derived from Cannabis sativa, exerts
a variety of therapeutic actions, such as anti-inflammatory, antioxidant, and antibacterial …
a variety of therapeutic actions, such as anti-inflammatory, antioxidant, and antibacterial …
Different Size Formulations of Fluopyram: Preparation, Antifungal Activity, and Accumulation in the Fungal Pathogen Botrytis cinerea
Y Wang, S Zhang, Y Xu, H Li, R Zhang, D Chen, J Xu… - Molecules, 2023 - mdpi.com
Nanotechnology is revolutionizing the efficient production and sustainable development of
modern agriculture. Understanding the pesticide activity of both nano-and conventional …
modern agriculture. Understanding the pesticide activity of both nano-and conventional …
[HTML][HTML] Nanosuspension Innovations: Expanding Horizons in Drug Delivery Techniques
Nanosuspensions (NS), with their submicron particle sizes and unique physicochemical
properties, provide a versatile solution for enhancing the administration of medications that …
properties, provide a versatile solution for enhancing the administration of medications that …
[HTML][HTML] Navigating translational research in nanomedicine: A strategic guide to formulation and manufacturing
Over the past two decades, extensive research has focused on both the fundamental and
applied aspects of nanomedicine, driven by the compelling advantages that nanoparticles …
applied aspects of nanomedicine, driven by the compelling advantages that nanoparticles …
Development of Dermal Lidocaine Nanosuspension Formulation by the Wet Milling Method Using Experimental Design: In Vitro/In Vivo Evaluation
O Kral, S Ilbasmis-Tamer, S Han, F Tirnaksiz - ACS omega, 2024 - ACS Publications
Lidocaine (LID), frequently used in dermal applications, is a nonpolar local anesthetic agent
that is practically insoluble in water. The main aim of this study is to develop the …
that is practically insoluble in water. The main aim of this study is to develop the …
Nanocrystal formulations of mebendazole employing quality by design and molecular level insights by atomistic simulations
E Vardaka, K Kachrimanis - Drug Development and Industrial …, 2024 - Taylor & Francis
Objective The present study investigates the production of mebendazole nanocrystal
formulations by wet media milling. Significance Nanocrystal formulations are expected to …
formulations by wet media milling. Significance Nanocrystal formulations are expected to …