Conspectus Chain-walking offers extensive opportunities for innovating synthetic methods
that involve constructing chemical bonds at unconventional sites. This approach provides …

This review aims to highlight the role of silicon in drug discovery. Silicon and carbon are
often regarded as being similar with silicon located directly beneath carbon in the same …

Organosilicon compounds have shown tremendous potential in drug discovery and their
synthesis stimulates wide interest. Multicomponent cross-coupling of alkenes with silicon …

The difunctionalization of unsaturated bonds plays a vital role in the enrichment of molecular
complexity. While various catalytic methods for alkene and alkyne difunctionalization have …

Single-atom site (SAS) catalysts have attracted considerable attention due to their excellent
performance. However, most of the current research models of SAS catalysts are based on …

While chiral allylic organophosphorus compounds are widely utilized in asymmetric
catalysis and for accessing bioactive molecules, their synthetic methods are still very limited …

Transition-metal-catalyzed sila-cycloaddition has been a promising tool for accessing
silacarbocycle derivatives, but the approach has been limited to a selection of well-defined …

Transition-metal catalyzed carbosilylation of alkenes using carbon electrophiles and
silylmetal (-B,-Zn) reagents as the nucleophiles offers a powerful strategy for synthesizing …

In this article, we disclose a method for the regiodivergent and stereoselective
hydrosilylation of isoprene using an Earth-abundant cobalt catalyst via variation of ligands …

Visible-light-mediated para-C–H difluoroalkylation of anilides via combination of steric
effects and Lewis acid activation strategies has been developed. The addition of (C 6 H 5 O) …