Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Stress often affects our social lives. When undergoing high-level or persistent stress,
individuals frequently retract from social interactions and become irritable and hostile …

Mounting evidence suggests that acute and chronic stress, especially the stress-induced
release of glucocorticoids, induces changes in glutamate neurotransmission in the prefrontal …

In response to stress, the brain activates several neuropeptide-secreting systems. This
eventually leads to the release of adrenal corticosteroid hormones, which subsequently feed …

Bruce McEwen's discovery of receptors for corticosterone in the rat hippocampus introduced
higher brain circuits in the neuroendocrinology of stress. Subsequently, these receptors …

Chronic stress could trigger maladaptive changes associated with stress-related mental
disorders; however, the underlying mechanisms remain elusive. In this study, we found that …

Brain cells are continuously exposed to corticosteroid hormones, although the levels vary
(eg, after stress). Corticosteroids alter neural activity via two receptor types …

The existence of U-shaped dose dependencies has been known for a long time. With regard
to corticosteroid action in brain cells, a dual receptor system that works in opposing …

In normal life, organisms are repeatedly exposed to brief periods of stress, most of which can
be controlled and adequately dealt with. The presently available data indicate that such brief …

It has become increasingly clear that the increase in corticosteroid levels, eg after a brief
stressor induce molecular and cellular changes in brain, including the hippocampal …