The endocrine function of human placenta: an overview

MA Costa - Reproductive biomedicine online, 2016‏ - Elsevier
During pregnancy, several tightly coordinated and regulated processes take place to enable
proper fetal development and gestational success. The formation and development of the …

[HTML][HTML] HELLP syndrome—holistic insight into pathophysiology

A Petca, BC Miron, I Pacu, MC Dumitrașcu… - Medicina, 2022‏ - mdpi.com
HELLP syndrome, also known as the syndrome of hemolysis, elevated liver enzymes, and
low platelets, represents a severe pregnancy complication typically associated with …

Noninvasive in vivo monitoring of tissue-specific global gene expression in humans

W Koh, W Pan, C Gawad, HC Fan, GA Kerchner… - Proceedings of the …, 2014‏ - pnas.org
Circulating cell-free RNA in the blood provides a potential window into the health,
phenotype, and developmental programs of a variety of human organs. We used high …

EASL Clinical Practice Guidelines on the management of liver diseases in pregnancy

C Williamson, M Nana, L Poon, L Kupcinskas… - Journal of …, 2023‏ - Elsevier
Liver diseases in pregnancy comprise both gestational liver disorders and acute and chronic
hepatic disorders occurring coincidentally in pregnancy. Whether related to pregnancy or …

Pathogenesis of the syndrome of hemolysis, elevated liver enzymes, and low platelet count (HELLP): a review

U Abildgaard, K Heimdal - European Journal of Obstetrics & Gynecology …, 2013‏ - Elsevier
HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome is serious for
the mother and the offspring. HELLP occurs in 0.2–0.8% of pregnancies and in 70–80% of …

Integrated systems biology approach identifies novel maternal and placental pathways of preeclampsia

NG Than, R Romero, AL Tarca, KA Kekesi… - Frontiers in …, 2018‏ - frontiersin.org
Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our
understanding of the complex interactions among their respective disease pathways …

The role of galectins as modulators of metabolism and inflammation

MF Brinchmann, DM Patel… - Mediators of …, 2018‏ - Wiley Online Library
Galectins are β‐galcotosid‐binding lectins. The function of galectins varies with their tissue‐
specific and subcellular location, and their binding to carbohydrates makes them key players …

Genetic aspects of preeclampsia and the HELLP syndrome

K Haram, JH Mortensen, B Nagy - Journal of pregnancy, 2014‏ - Wiley Online Library
Both preeclampsia and the HELLP syndrome have their origin in the placenta. The aim of
this study is to review genetic factors involved in development of preeclampsia and the …

A primate subfamily of galectins expressed at the maternal–fetal interface that promote immune cell death

NG Than, R Romero, M Goodman, A Weckle… - Proceedings of the …, 2009‏ - pnas.org
Galectins are proteins that regulate immune responses through the recognition of cell-
surface glycans. We present evidence that 16 human galectin genes are expressed at the …

Late-onset preeclampsia is associated with an imbalance of angiogenic and anti-angiogenic factors in patients with and without placental lesions consistent with …

E Soto, R Romero, JP Kusanovic, G Ogge… - The Journal of …, 2012‏ - Taylor & Francis
Objective: An imbalance between maternal angiogenic/anti-angiogenic factors
concentrations has been observed in preeclampsia (PE) and other obstetrical syndromes …