Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis

C Wacker, A Prkno, FM Brunkhorst… - The Lancet infectious …, 2013 - thelancet.com
Background Procalcitonin is a promising marker for identification of bacterial infections. We
assessed the accuracy and clinical value of procalcitonin for diagnosis of sepsis in critically …

Diagnostic and prognostic biomarkers of sepsis in critical care

S Kibe, K Adams, G Barlow - Journal of antimicrobial …, 2011 - academic.oup.com
Sepsis is a leading cause of mortality in critically ill patients. Delay in diagnosis and initiation
of antibiotics have been shown to increase mortality in this cohort. However, differentiating …

Procalcitonin-guided algorithms of antibiotic therapy in the intensive care unit: a systematic review and meta-analysis of randomized controlled trials

P Kopterides, II Siempos, I Tsangaris… - Critical care …, 2010 - journals.lww.com
Objective: There is increasing interest for strategies that could curtail antibiotic resistance in
the critical care setting. We sought to determine the effectiveness and safety of procalcitonin …

Biomarkers for diagnosis of sepsis in patients with systemic inflammatory response syndrome: a systematic review and meta-analysis

Y Liu, J Hou, Q Li, K Chen, SN Wang, J Wang - Springerplus, 2016 - Springer
Background Sepsis is one of the most common diseases that seriously threaten human
health. Although a large number of markers related to sepsis have been reported in the last …

Discriminative value of inflammatory biomarkers for suspected sepsis

EL Tsalik, LB Jaggers, SW Glickman… - The Journal of …, 2012 - Elsevier
BACKGROUND: Circulating biomarkers can facilitate sepsis diagnosis, enabling early
management and improved outcomes. Procalcitonin (PCT) has been suggested to have …

Sepsis: from pathophysiology to individualized patient care

I László, D Trásy, Z Molnár… - Journal of immunology …, 2015 - Wiley Online Library
Sepsis has become a major health economic issue, with more patients dying in hospitals
due to sepsis related complications compared to breast and colorectal cancer together …

The efficacy of procalcitonin as a biomarker in the management of sepsis: slaying dragons or tilting at windmills?

P Sridharan, RS Chamberlain - Surgical infections, 2013 - liebertpub.com
Background: Sepsis is defined as systemic inflammatory response syndrome (SIRS) in the
context of an underlying infectious process, and is associated with high rates of morbidity …

Reliability of admission procalcitonin testing for capturing bacteremia across the sepsis spectrum: real-world utilization and performance characteristics, 65 US …

A Lawandi, M Oshiro, S Warner, G Diao… - Critical care …, 2023 - journals.lww.com
OBJECTIVES: Serum procalcitonin is often ordered at admission for patients with suspected
sepsis and bloodstream infections (BSIs), although its performance characteristics in this …

Role of procalcitonin in managing adult patients with respiratory tract infections

P Schuetz, DN Amin, JL Greenwald - Chest, 2012 - Elsevier
Respiratory infections remain the most common reason why patients seek medical care in
ambulatory and hospital settings, and they are the most frequent precursor of sepsis. In light …

Benefit of hemoadsorption therapy in patients suffering sepsis-associated acute kidney injury: a case series

MS Hakemi, AA Nassiri, A Nobakht, M Mardani… - Blood …, 2022 - karger.com
Introduction: Sepsis is defined as life-threatening organ dysfunction in result of the host's
dysregulated response to infection and septic shock. Sepsis-associated kidney injury is …