[HTML][HTML] Proteomics-driven biomarkers in Pancreatic Cancer

L Ramalhete, E Vigia, R Araújo, HP Marques - Proteomes, 2023 - mdpi.com
Pancreatic cancer is a devastating disease that has a grim prognosis, highlighting the need
for improved screening, diagnosis, and treatment strategies. Currently, the sole biomarker …

Community detection in protein-protein interaction networks and applications

I Manipur, M Giordano, M Piccirillo… - IEEE/ACM …, 2021 - ieeexplore.ieee.org
The ability to identify and characterize not only the protein-protein interactions but also their
internal modular organization through network analysis is fundamental for understanding …

Clustering and summarizing protein-protein interaction networks: A survey

SS Bhowmick, BS Seah - IEEE Transactions on Knowledge …, 2015 - ieeexplore.ieee.org
The increasing availability and significance of large-scale protein-protein interaction (ppi)
data has resulted in a flurry of research activity to comprehend the organization, processes …

Decision tree classifier based on topological characteristics of subgraph for the mining of protein complexes from large scale PPI networks

TR Sahoo, S Patra, S Vipsita - Computational Biology and Chemistry, 2023 - Elsevier
The growing accessibility of large-scale protein interaction data demands extensive
research to understand cell organization and its functioning at the network level …

PC2P: parameter-free network-based prediction of protein complexes

S Omranian, A Angeleska, Z Nikoloski - Bioinformatics, 2021 - academic.oup.com
Motivation Prediction of protein complexes from protein–protein interaction (PPI) networks is
an important problem in systems biology, as they control different cellular functions. The …

IoMT-based association rule mining for the prediction of human protein complexes

M Sikarndar, W Anwar, A Almogren, IU Din… - IEEE …, 2020 - ieeexplore.ieee.org
The inspiring increase in the Internet-enabling devices has influenced health industry due to
the nature of these devices where they offer health related information swiftly. One of the …

[PDF][PDF] On knowledge discovery and interactive intelligent visualization of biomedical data

A Holzinger - Proceedings of the Int. Conf. on Data …, 2012 - graz.elsevierpure.com
Biomedical Informatics can be defined as “the interdisciplinary field that studies and pursues
the effective use of biomedical data, information and knowledge for scientific inquiry …

Using PPI network autocorrelation in hierarchical multi-label classification trees for gene function prediction

D Stojanova, M Ceci, D Malerba, S Dzeroski - BMC bioinformatics, 2013 - Springer
Background Ontologies and catalogs of gene functions, such as the Gene Ontology (GO)
and MIPS-FUN, assume that functional classes are organized hierarchically, that is, general …

HetFCM: functional co-module discovery by heterogeneous network co-clustering

H Tan, M Guo, J Chen, J Wang, G Yu - Nucleic Acids Research, 2024 - academic.oup.com
Functional molecular module (ie, gene–miRNA co-modules and gene–miRNA–lncRNA
triple-layer modules) analysis can dissect complex regulations underlying etiology or …

Super. Complex: A supervised machine learning pipeline for molecular complex detection in protein-interaction networks

MV Palukuri, EM Marcotte - PloS one, 2021 - journals.plos.org
Characterization of protein complexes, ie sets of proteins assembling into a single larger
physical entity, is important, as such assemblies play many essential roles in cells such as …