[HTML][HTML] Brain-derived neurotrophic factor: a key molecule for memory in the healthy and the pathological brain

M Miranda, JF Morici, MB Zanoni… - Frontiers in cellular …, 2019 - frontiersin.org
Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

B Lu, G Nagappan, X Guan, PJ Nathan… - Nature Reviews …, 2013 - nature.com
Increasing evidence suggests that synaptic dysfunction is a key pathophysiological hallmark
in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of …

Potential therapeutic uses of BDNF in neurological and psychiatric disorders

AH Nagahara, MH Tuszynski - Nature reviews Drug discovery, 2011 - nature.com
The growth factor brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy

M Notaras, R Hill, M van den Buuse - Molecular psychiatry, 2015 - nature.com
Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development,
differentiation and plasticity in both the develo** and adult brain. A single-nucleotide …

BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex

JA Kleim, S Chan, E Pringle, K Schallert… - Nature …, 2006 - nature.com
Motor training can induce profound physiological plasticity within primary motor cortex,
including changes in corticospinal output and motor map topography. Using transcranial …

Brain-derived neurotrophic factor (BDNF): novel insights into regulation and genetic variation

M Notaras, M van den Buuse - The Neuroscientist, 2019 - journals.sagepub.com
Since its discovery, brain-derived neurotrophic factor (BDNF) has spawned a literature that
now spans 35 years of research. While all neurotrophins share considerable overlap in …

Chemobrain: a critical review and causal hypothesis of link between cytokines and epigenetic reprogramming associated with chemotherapy

XM Wang, B Walitt, L Saligan, AFY Tiwari, CW Cheung… - Cytokine, 2015 - Elsevier
One consequence of modern cancer therapy is chemotherapy related cognitive dysfunction
or “chemobrain”, the subjective experience of cognitive deficits at any point during or …

BDNF and schizophrenia: from neurodevelopment to neuronal plasticity, learning, and memory

R Nieto, M Kukuljan, H Silva - Frontiers in psychiatry, 2013 - frontiersin.org
Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin that has been related not only
to neurodevelopment and neuroprotection, but also to synapse regulation, learning, and …

[HTML][HTML] New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brain-related diseases

N Adachi, T Numakawa, M Richards… - World journal of …, 2014 - ncbi.nlm.nih.gov
Brain-derived neurotrophic factor (BDNF) attracts increasing attention from both research
and clinical fields because of its important functions in the central nervous system. An …

Brain-derived neurotrophic factor and schizophrenia

P Di Carlo, G Punzi, G Ursini - Psychiatric genetics, 2019 - journals.lww.com
The brain-derived neurotrophic factor (BDNF) is a secretory growth factor that promotes
neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the …