An audit of uncertainty in multi-scale cardiac electrophysiology models

RH Clayton, Y Aboelkassem… - … of the Royal …, 2020 - royalsocietypublishing.org
Models of electrical activation and recovery in cardiac cells and tissue have become
valuable research tools, and are beginning to be used in safety-critical applications …

A comprehensive mathematical model for cardiac perfusion

A Zingaro, C Vergara, L Dede', F Regazzoni… - Scientific Reports, 2023 - nature.com
The aim of this paper is to introduce a new mathematical model that simulates myocardial
blood perfusion that accounts for multiscale and multiphysics features. Our model …

Branched latent neural maps

M Salvador, AL Marsden - Computer Methods in Applied Mechanics and …, 2024 - Elsevier
Abstract We introduce Branched Latent Neural Maps (BLNMs) to learn finite dimensional
input–output maps encoding complex physical processes. A BLNM is defined by a simple …

[HTML][HTML] Boundary integral formulation of the cell-by-cell model of cardiac electrophysiology

GR de Souza, R Krause, S Pezzuto - Engineering Analysis with Boundary …, 2024 - Elsevier
We propose a boundary element method for the accurate solution of the cell-by-cell
bidomain model of electrophysiology. The cell-by-cell model, also called Extracellular …

Effects of cardiac growth on electrical dyssynchrony in the single ventricle patient

OZ Tikenoğulları, M Peirlinck, H Chubb… - Computer methods in …, 2024 - Taylor & Francis
Single ventricle patients, including those with hypoplastic left heart syndrome (HLHS),
typically undergo three palliative heart surgeries culminating in the Fontan procedure. HLHS …

Experimental validation of a variational data assimilation procedure for estimating space-dependent cardiac conductivities

A Barone, A Gizzi, F Fenton, S Filippi… - Computer Methods in …, 2020 - Elsevier
Customization of mathematical and numerical models to patient-specific settings is a critical
step of the translation process bringing scientific computing to the clinical activity. In …

Fast uncertainty quantification of activation sequences in patient‐specific cardiac electrophysiology meeting clinical time constraints

A Quaglino, S Pezzuto… - … journal for numerical …, 2018 - Wiley Online Library
We present a fast, patient‐specific methodology for uncertainty quantification in
electrophysiology, aimed at meeting the time constraints of clinical practitioners. We focus …

A curvilinear isogeometric framework for the electromechanical activation of thin muscular tissues

A Nitti, J Kiendl, A Gizzi, A Reali, MD de Tullio - Computer Methods in …, 2021 - Elsevier
We propose an isogeometric approximation of the equations describing the propagation of
an electrophysiologic stimulus over a thin cardiac tissue with the subsequent muscle …

Evaluation of a rapid anisotropic model for ECG simulation

S Pezzuto, P Kal'avský, M Potse, FW Prinzen… - Frontiers in …, 2017 - frontiersin.org
State-of-the-art cardiac electrophysiology models that are able to deliver physiologically
motivated activation maps and electrocardiograms (ECGs) can only be solved on high …

Fast characterization of inducible regions of atrial fibrillation models with multi-fidelity Gaussian process classification

L Gander, S Pezzuto, A Gharaviri, R Krause… - Frontiers in …, 2022 - frontiersin.org
Computational models of atrial fibrillation have successfully been used to predict optimal
ablation sites. A critical step to assess the effect of an ablation pattern is to pace the model …